Titlebook: Bioinformatics Research and Applications; 13th International S Zhipeng Cai,Ovidiu Daescu,Min Li Conference proceedings 2017 Springer Nature

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A New 2-Approximation Algorithm for rSPR Distance,the set of species. In this case, we want to measure the dissimilarity of the two trees. The rooted subtree prune and regraft (rSPR) distance of the two trees has been used for this purpose. The problem of computing the rSPR distance of two given trees has many applications but is NP-hard. The previ

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An SIMD Algorithm for Wraparound Tandem Alignment,mechanisms and are useful for forensics studies. The need to quickly analyze high volumes of sequencing data for TRs and VNTRs has motivated the search for a more efficient sequence alignment algorithm for tandem repeats. Alignment of a pattern to a sequence, which may contain zero or more tandem co

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PhAT-QTL: A Phase-Aware Test for QTL Detection,th dense genetic data, quantitative trait loci (QTL) mapping of molecular traits is a fundamental tool for understanding the genetic basis of gene regulation. However, standard computational approaches for QTL mapping ignore the diploid nature of human genomes, testing for association between genoty

OGLE

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Genetic Algorithm Based Beta-Barrel Detection for Medium Resolution Cryo-EM Density Maps, interactions and structures of those molecules. Identifying the secondary structures (α-helices and β-sheets) located in proteins using density maps is vital in identifying and matching the backbone of the protein with the cryo-EM density map. The β-barrel is a unique β-sheet structure commonly fou

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Coestimation of Gene Trees and Reconciliations Under a Duplication-Loss-Coalescence Model,most popular algorithms consider only a restricted set of evolutionary events, typically modeling only duplications and losses or only coalescences. Recent work has unified duplications, losses, and coalescences through an intermediate locus tree; however, the associated reconciliation algorithms as

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0302-9743 plications, ISBRA 2017, held in Honolulu, HI, USA, in May/June 2017. .The 27 full papers presented together with 18 short papers and 24 invited abstracts were carefully reviewed and selected from 131 submissions. They cover topics such as: biomarker discovery; biomedical databases and data integrati