Titlebook: Bioinformatics Methods in Clinical Research; Rune Matthiesen Book 2010 Humana Press 2010 Annotation.An?sthesie-Informations-Management-Sys

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Overview on Techniques in Cluster Analysis,ny contexts and disciplines. Cluster analysis encompasses different methods and algorithms for grouping objects of similar kinds into respective categories. In this chapter, we describe a number of methods and algorithms for cluster analysis in a stepwise framework. The steps of a typical clustering

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Nonalcoholic Steatohepatitis, Animal Models, and Biomarkers: What Is New?,ccumulation in the hepatocytes (hepatic steatosis) to hepatic steatosis with inflammation (steatohepatitis, also known as nonalcoholic steatohepatitis or NASH). NASH can also progress to cirrhosis and hepatocellular carcinoma (HCC). Steatohepatitis has been estimated to affect around 5% of the total

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Biomarkers in Breast Cancer,er at the molecular level have arisen from microarray data. Molecular profiling has supported the notion that breast cancer is not a simple disease with a single tumorigenic pathway but a rather heterogeneous one. Gene expression studies have identified and validated the existence of different breas

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Genome-Wide Proximal Promoter Analysis and Interpretation,complex molecular descriptions generated by these approaches is still challenging. The development of new methodologies to identify common regulatory mechanisms involved in the control of the expression of a set of co-expressed genes might enhance our capacity to extract functional information from

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Methods and Algorithms for Relative Quantitative Proteomics by Mass Spectrometry,roteins and their posttranslational modifications in one experiment. In contrast, protein arrays only provide quantitative values of targeted proteins and their modifications. There are an overwhelming number of quantitative mass spectrometry (MS) methods for protein and peptide quantitation. The ai