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Titlebook: Bioconjugation; Methods and Protocol Sam Massa,Nick Devoogdt Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 P

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發(fā)表于 2025-3-21 19:32:39 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Bioconjugation
期刊簡稱Methods and Protocol
影響因子2023Sam Massa,Nick Devoogdt
視頻videohttp://file.papertrans.cn/187/186765/186765.mp4
發(fā)行地址Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts
學科分類Methods in Molecular Biology
圖書封面Titlebook: Bioconjugation; Methods and Protocol Sam Massa,Nick Devoogdt Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 P
影響因子This book explores well-established and emerging conjugation strategies that are relevant for proteins used in the field of precision medicine, focusing on techniques that are suitable for antibodies, antibody-fragments such as Fabs, scFvs, or nanobodies, scaffold proteins such as FN3 or DARPin, peptides, or model proteins. Although centered on the development of bioconjugates rather than their application, most protocols also show the conjugation of the targeting vehicle to a diagnostic or therapeutic entity, with the end-product most often being an antibody-drug conjugate, an optical probe, a nanomedicine, or a radiopharmaceutical. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.?.Authoritative and practical, .Bioconjugation: Methods and Protocols. is an ideal guide for researchers looking toward precision medicine in order to expand the vital field of drug discovery..
Pindex Book 2019
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書目名稱Bioconjugation影響因子(影響力)




書目名稱Bioconjugation影響因子(影響力)學科排名




書目名稱Bioconjugation網絡公開度




書目名稱Bioconjugation網絡公開度學科排名




書目名稱Bioconjugation被引頻次




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書目名稱Bioconjugation年度引用




書目名稱Bioconjugation年度引用學科排名




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書目名稱Bioconjugation讀者反饋學科排名




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發(fā)表于 2025-3-21 20:54:23 | 只看該作者
Methods in Molecular Biologyhttp://image.papertrans.cn/b/image/186765.jpg
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978-1-4939-9656-8Springer Science+Business Media, LLC, part of Springer Nature 2019
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https://doi.org/10.1007/978-3-531-18989-5ical ingredients (HPAPIs) selectively to tumor tissue. So far, HPAPIs have been mainly attached to the antibody via a chemical reaction of the payload with lysine or cysteine side chains of the antibody backbone. However, these conventional conjugation technologies result in formation of rather hete
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https://doi.org/10.1007/978-3-662-63117-1rmacological characteristics. We have developed a strategy to produce site-specific ADCs using a highly reactive lysine residue embedded in a dual-variable-domain (DVD) format. Here we provide protocols for the engineering, expression, and purification of the DVDs used for this strategy. We also pro
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,Künstliche Stimulanzien der Kreativit?t, drug-to-antibody ratios. One approach for generating homogeneous antibody conjugates utilizes enzymatic transfer of payloads onto a specific glycan or amino acid residue. Microbial transglutaminase (MTG) is an enzyme that catalyzes the formation of a stable isopeptide bond between a glutamine and a
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