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Titlebook: Biochemistry of Pulmonary Emphysema; C. Grassi,J. Travis,M. Luisetti Book 1992 Springer-Verlag London 1992 Alpha1-Proteinase Inhibitor.Lun

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發(fā)表于 2025-3-21 17:09:54 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Biochemistry of Pulmonary Emphysema
影響因子2023C. Grassi,J. Travis,M. Luisetti
視頻videohttp://file.papertrans.cn/187/186720/186720.mp4
學(xué)科分類Current Topics in Rehabilitation
圖書封面Titlebook: Biochemistry of Pulmonary Emphysema;  C. Grassi,J. Travis,M. Luisetti Book 1992 Springer-Verlag London 1992 Alpha1-Proteinase Inhibitor.Lun
影響因子Pulmonary emphysema is a disease which develops because of a localized imbalance between endogenous proteinase inhibitors and proteinases leaking from neurophils during phagocytosis at inflammatory foci within the lung. This volume not only reviews at a biochemical level what is known about the natural inhibitors and proteinases involved in connective tissue destruction within the lung, but also suggests novel methodologies for reestablishing proper enzyme-inhibitor balance, including the use of natural or synthetic inhibitors for supplementation or gene therapy.
Pindex Book 1992
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Synthetic Mechanism-Based and Transition-State Inhibitors for Human Neutrophil Elastase,old in the lungs of smokers and it is postulated that α.PI is inactivated by powerful oxidizing agents in the cigarette smoke and PMNs contributing to the elastase-antielastase imbalance. Other proteases including human proteinase 3 and macrophage elastase may also play a role in lung destruction in
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Genetic Control of Human Alpha-1-Antitrypsin and Hepatic Gene Therapy,sin, thrombin, kallikrein, and plasmin., its apparent major physiological role is to diffuse into the alveoli structure of the lung, and protect elastin fibres from excessive hydrolysis by neutrophil elastase.. Neutrophil elastase is inhibited by forming a pseudo-irreversible equimolar complex of the protease with inhibitor..
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Book 1992ral inhibitors and proteinases involved in connective tissue destruction within the lung, but also suggests novel methodologies for reestablishing proper enzyme-inhibitor balance, including the use of natural or synthetic inhibitors for supplementation or gene therapy.
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Kostenrechnung in Klein- und Mittelbetriebenal and venous elements, lymphatics, and the pleura. The unusual hydrophobic properties of the protein, together with the presence of numerous intermolecular crosslinks, in particular desmosine and isodesmosine, produce a highly insoluble, durable network of polypeptide chains that function as a perfect elastomer in an aqueous environment.
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