Titlebook: Biochemistry of Cell Membranes; A Compendium of Sele S. Papa,J. M. Tager Book 1995 Birkh?user Verlag 1995 ATP.Biochemie.Calcium.DNA.Zellbio

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Molecular structure of G protein-coupled P2 purinoceptorsIn this chapter the recent cloning of cDNAs encoding G protein-coupled purinoceptors for ATP and other nucleotides is reviewed. This has revealed that they form a new family within this receptor superfamily.

Medley

Protein import into mitochondriaThe key to the biogenesis of mitochondria is the import and sorting of cytosolically synthesized proteins to their final sub-mitochondrial destination. This review summarizes recent progress in our understanding of these processes and formulates some of the many questions to be answered in the field.

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The role of p21ras in receptor tyrosine kinase signalingently, progress has been made in the elucidation of this signaling pathway. After a ligand binds to most, if not all, receptor tyrosine kinases, a guanine nucleotide exchange factor is activated, which brings p21ras in the GTP-bound form. This GTP-bound form of p21ras interacts with the protein kina

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RAS proteins and control of the cell cycle in,nd Marshall, 1989; Broach and Deschenes, 1990). According to the rules of yeast genetics (dominant genes are indicated by three capital letters followed by a number), the yeast genes were denominated . and . (collectively referred to as .). The corresponding RAS1 and RAS2 proteins were 309 and 322 a

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Translocation of bacterial protein toxins across membranesess which consists of: (1) binding, (2) internalization, (3) membrane translocation, and (4) target modification. All of them form ion channels across planar lipid bilayers and plasma membrane of cells. A relation between ion channel and membrane translocation may be inferred and two different model

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Role of the GTP/GDP switch for the function of rab5 in endocytosis is bound. Here, we discuss the role of the nucleotide state for the function of rab5, which operates in the early endocytic pathway. Regions involved in nucleotide dependent conformational changes contribute to functionally distinguish rab5 from rab6. Furthermore, mutational analysis of rab5 sugges

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Regulation of autophagyintracellular protein occurs in the lysosomes and is mediated by autophagy. Factors controlling autophagy, including amino acids, insulin, glucagon and cell volume, have opposite effects on protein synthesis. Recent evidence indicates that lysosomal protein degradation can be selective and occurs vi