Titlebook: Biochemistry of Arachidonic Acid Metabolism; William E. M. Lands Book 1985 Martinus Nijhoff Publishing, Boston 1985 Lipid.Nucleotide.bioch

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Lipoxygenase Mechanisms,conjugated diene system is a required structure of all substrate fatty acids. The usual product from the action of animal and plant lipoxygenases upon such substrates is a .-conjugated hydroperoxy acid (Figure 1). The action of lipoxygenases upon substrate fatty acids is commonly monitored by polaro

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Enzymes Synthesizing and Metabolizing Prostanoids,thesized by a series of enzymes; phospholipases, fatty acid cyclooxygenase (Fig. 1 [1]), PG hydro-peroxidase ([2]) and various endoperoxide-metabolizing enzymes. The first three enzymes are considered to be present in all the prostanoid-synthesizing tissues, and PGH. with a 9, 11-endoperoxide is pro

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Role of Active Oxygen in the Formation of Lipid Hydroperoxides,een the incidence of breast and colon carcinomas and the per capita consumption of fat (1,2). There appears to be some distinction between the effects of saturated and unsaturated fats. Carroll and his group demonstrated that polyunsaturated fats were more effective than saturated fats in promoting

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Radiation Effects on Eicosanoid Formation,This includes the various ranges of ultraviolet (UV) and the ionizing radiation, gamma and X-ray. The literature indicates that all these forms of radiation potentially alter the anabolism and perhaps the catabolism of the prostaglandins. These alterations manifest as either increases or decreases i

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Phospholipases, a major role in the catabolism of dietary lipids for energy sources and also are important in the metabolism of membrane structural phospholipids. This latter function contributes to the control of each cell type’s unique phospholipid composition and undoubtedly has a major role in regulating cell