Titlebook: Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science; J. Robin Harris,Viktor I. Korolchuk Book 2023 The Editor(s) (if applic

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Enervate

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Chronic Inflammation as an Underlying Mechanism of Ageing and Ageing-Related Diseases,ed diseases. In this chapter, we review the age-related changes in the oxidative stress-sensitive pro-inflammatory NF-κB signaling pathways causally linked with chronic inflammation during ageing based on senoinflammation schema. We describe various age-related dysregulated pro- and anti-inflammator

Torrid

Heart Disease and Ageing: The Roles of Senescence, Mitochondria, and Telomerase in Cardiovascular Dtic instability and chronic inflammation, which contribute to the development and progression of ageing-associated diseases including cardiovascular disease. Consequently, understanding how these hallmarks of biological ageing interact with the cardiovascular system and each other is fundamental to

擔(dān)心

Chronic Kidney Disease and the Exposome of Ageing, ‘.’, typified by a range of non-communicable diseases which share a common underlying component of a dysregulated ageing process. Within this, chronic kidney disease is an emerging global epidemic..The extensive inter-individual variation displayed in how people age and how their diseasome manifest

Repatriate

Sarcopenia and Ageing,nia that is characterized by progressive and generalized loss of skeletal muscle mass and strength with a risk of adverse outcomes. In recent years, a few consensus panels provide new definitions for sarcopenia. It was officially recognized as a disease in 2016 with an ICD-10-CM disease code, M62.84

Mortar

Tendon Aging,t of the body, yet, with advancing age, tendons become more prone to degeneration followed by injuries. Tendon diseases are one of the main causes of incapacity worldwide, leading to changes in tendon composition, structure, and biomechanical properties, as well as a decline in regenerative potentia

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Virus Infections in Older People,oportionate number of deaths occurred in the oldest and frailest people. The assessment of the older person with a viral infection is complicated by the high prevalence of multiple comorbidities and sensory or cognitive impairment. They often present with common geriatric syndromes such as falls or

PRISE

Models and Biomarkers for Ovarian Ageing,ining age at menopause for healthy women. In this chapter, the concept of ovarian reserve is explored in detail, with a sequence of models described that in principle allow any individual to be compared to the general population. As there is no current technology that can count the NGFs in a living

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