Titlebook: Biochemical Roles of Eukaryotic Cell Surface Macromolecules; 2011 ISCSM Proceedin Perumana R. Sudhakaran,Avadhesha Surolia Conference proce

Excitotoxin

Lactosylceramide Synthase as a Therapeutic Target to Mitigate Multiple Human Diseases in Animal Mod developments in this area of research point to the suggestion that many physiological molecules can activate this enzyme to generate a glycosphingolipid (GSL), lactosylceramide (LacCer), which can induce critical phenotypes such as cell proliferation, migration, adhesion, angiogenesis, and apoptosi

Tremor

restrain

Mechanism of GPCR-Directed Autoantibodies in Diseases,several human pathologies. For example, autoimmune pathogenesis of Graves’ disease is attributed to autoantibody-mediated activation of the thyrotropin receptor, a GPCR. Likewise, diseases such as preeclampsia and vascular allograft rejection are caused by autoantibodies against angiotensin II type

Gratulate

dialect

Ossification

Apoptosis of Breast Cancer Cells: Modulation of Genes for Glycoconjugate Biosynthesis and Targeted lecules. The Lea, Leb, LeX, LeY, and their sialosyl-derivatives, all .-acetylglucosaminyl-containing glycoconjugate antigens, are overexpressed on the surfaces of breast, colon, and ovarian cancer cells during metastasis. A few inhibitors of GSLs (.-/.-PPMP) and DNA (cisplatin) biosynthesis, betulin

FAST

飛行員

Poly-ADP-Ribosylation of Vascular Endothelial Growth Factor and Its Implications on Angiogenesis, dependent signaling events. Apart from glycosylation, a key posttranslational modification of VEGF involves polyADP ribosylation. While glycosylation is critical in its secretion, PAR modification is not critical for its secretion as evidenced by absence of any significant effect of 3-aminobenzamid

熱烈的歡迎

Sphingolipid-Binding Domain in the Serotonin1A Receptor,sphingolipid organization in cellular membranes is their segregation in membrane domains. Serotonin. receptors are representative members of the superfamily of G-protein coupled receptors (GPCRs) and are implicated in the generation and modulation of various cognitive, developmental, and behavioral

機(jī)警

Conference proceedings 2012cules, particularly glycoconjugates are presented in this book. Comprising of 22 chapters from the 2011 International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules, it covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoco