Titlebook: Biochemical Approaches for Glutamatergic Neurotransmission; Sandrine Parrot,Luc Denoroy Book 2018 Springer Science+Business Media LLC 2018

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Bürgerfunk als Vielfaltsreserveto long-term neuronal damage seen in many neurological disorders, including traumatic brain injury (TBI) and stroke. Therefore, methods for continuous monitoring of extracellular Glu concentrations in the brain can be very useful to clinicians for determining the best timing for pharmacological inte

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https://doi.org/10.1007/978-3-658-02417-8 microdialysis coupled to a separation micro-method, such an approach offering high chemical selectivity combined to good anatomical and temporal resolution. Among the two separation micro-methods used to determine glutamate in brain microdialysates, namely liquid chromatography and capillary electr

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https://doi.org/10.1007/978-3-658-02417-8hich induce neuronal dysfunctions and neurological diseases. An evaluation of in vivo glutamate transport can enable to verify the functional impact of alterations previously found in in vitro and ex vivo preparations. The use of brain microdialysis to sample the extracellular medium has allowed to

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https://doi.org/10.1007/978-3-531-91562-3inical studies, the monitoring of glutamate has revealed tight links between the variations of its interstitial concentration and those of other metabolic biomarkers and partial pressure in oxygen within tissue. The use of microdialysis has allowed to monitor glutamate over several days in patients

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Sandrine Parrot,Luc DenoroyIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts

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Biochemical Approaches for Glutamatergic Neurotransmission