Titlebook: Bioassays in Experimental and Preclinical Pharmacology; Karuppusamy Arunachalam,Sreeja Puthanpura Sasidhar Book 2021 The Editor(s) (if app

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Phytochemical Analysis,s and hence various levels of research are concentrated on it. This chapter deals with the quantitative and qualitative analyses of different metabolites like total phenolics, flavonoids, saponins, tannins and phytosterols. In detail, the Folin-Ciocalteu colourimetric assay to analyse the total phen

偽證

Preclinical Drug Dose Calculation,art in drug research, is significant as it varies among species. Hence the pharmacokinetics and pharmacodynamics need to consider on dose fixation and various methods are available for this, few of which are described in this chapter. The conversion based on normalization of dose-to-body surface are

Lignans

Toxicology Studies: In Vitro and In Vivo,l lines with the measurement of cell damage and an in vivo studies comprising acute and sub-acute toxicity steps using animals are well described in this chapter with detailed formulas and tables. Alamar Blue method, micronucleus and comet tests evaluating the chromosome/DNA level damage and analysi

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Animal Experiments on the Cardiovascular System,sk factors, while its treatment relies on reducing the risk factors like lowering bad cholesterol and reducing blood pressure (BP). This chapter deals with the various protocols related to the risk factors of cardiovascular disease that include the procedures like obtaining electrocardiogram (ECG) a

cardiovascular

Libido

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Experiments of Antifungal Activities,tory concentration (MIC) and the minimum fungicidal concentration (MFC) are determined by the broth microdilution techniques while the synergistic antimicrobial activity of the tested complexes combined with two antifungal drugs (ketoconazole and amphotericin B) made by checkerboard and biofilm assa