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Titlebook: Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular; Eric Reid,J. D. Robinson,Ian D. Wilson Book 1988 Sp

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發(fā)表于 2025-3-21 18:16:25 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular
影響因子2023Eric Reid,J. D. Robinson,Ian D. Wilson
視頻videohttp://file.papertrans.cn/187/186486/186486.mp4
學科分類Methodological Surveys in Biochemistry and Analysis
圖書封面Titlebook: Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular;  Eric Reid,J. D. Robinson,Ian D. Wilson Book 1988 Sp
影響因子vi as did non-appreciation that % values for bought-in solutions (notably ammonia) may be on a weight basis, not made evident by the manufacturer. Notwithstanding the shortcomings or lateness of some texts, authors are thanked for compiling them amidst other pressures. Elsevier and the American Chemical Society are also thanked, for Figures now reproduced with source acknowledgement. This Editor has generally respected authors‘ phrasing, whilst shuddering when the term ‘incubate‘ is encountered in a 0° context. He remains a ‘diehard‘ in certain respects, notably in favouring ‘M‘ rather than ‘mol/I‘, and a wt./ml basis for drug concentrations in test samples; he regards ‘mmol/l‘ as a fatuous fashion. Concerning infelicitous abbreviations, a distinction is made between electron- capture (detector context; ‘ECD‘) and electrochemical (‘EC‘, never ‘ECD‘); the hallowed GC term ‘FID‘ means free induction decay to NMR practi tione:ts, who may pardon the term ‘Fid‘ as introduced editorially. The convention for ,0C‘ throughout the book is ‘0‘. Undefined but well-known abbreviations include GC, HPLC and TLC. MS (mass spectrometry), NPD (nitrogen-phosphorus detector), tr (retention time) and R
Pindex Book 1988
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Analysis of Eicosanoids by GC-MS/MSlar substances often found in much higher concentration. Hence past assays of insufficient specificity have given erroneous values. GC-MS, which is more specific than RIA, is effective for structure elucidation and assay of eicosanoids and metabolites, yet may be insufficiently selective at low eico
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Quantitative Determination of Several Prostaglandins and Thromboxane B2 in the Isolated Perfused Rated rat brain, perfused with a synthetic fluoro-carbon perfusion medium. After perfusion, the brains were frozen in isopentane at ?56°, freeze-dried at ?40° and pulverized (liq. N.). The powder (~100 mg) was spiked with 4 deuterated analytes and extracted with methanol/water. The supernatants were ap
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Analytical Methods for [3H]-Enisoprost, an Anti-Secretory PGE1 Analogue, and its MetabolitesLRC* were used. These methods were scaled up to allow isolation and purification of urinary metabolites. These were identified by GC-MS of their ME-MO-TMS and PFB-MO-TMS derivatives. The latter provided mol. wt. data from the intense [M-PFB]. ions formed by NCI with ammonia, and the former provided
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Radioimmunoassay of Eicosanoids: Its Application in the Development of Anti-Inflammatory and Analgesy including regulation of microvascular blood flow and permeability, leukocyte chemotaxis, hyperalgesia and anaphylaxis. Consequently, in recent years considerable effort has been expended in the search for agents that block the synthesis and antagonize the actions of these autocoids. Most of the bi
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Analysis of the Actions of Anti-Inflammatory Drugs, with Particular Reference to Effects on Interleustimulated or unstimulated leucocytes. Assays developed for two main IL’s, viz. IL-1 and IL-2, include cell responses such as production of other mediators, or reactions (e.g. proliferation, aggregation) whose specificity depends on the responsiveness of the cell type as well as the purity of the ex
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Immunoassay of Beclomethasone 17,21-Dipropionate and Metabolites levels down to 0.1 (plasma) or 1 (urine) ng/ml. The 3-O-carboxymethyloxime derivative of BDP was coupled by a mixed-anhydride reaction to bovine serum albumin (BSA) for raising a rabbit antiserum, or to [..] iodohistamine to provide a radiolabel. Known BDP metabolites and endogenous steroids had ne
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