Titlebook: Bioactive Sphingolipids in Cancer Biology and Therapy; Yusuf A. Hannun,Chiara Luberto,Lina Marie Obeid Book 2015 Springer International Pu

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Role of Sphingolipids in Hematological Malignancies: Lymphoproliferative Disorderside, the putative different functions of ceramide species, and their metabolic regulation have been investigated in regard to induction of cell death of many types of cancers. Recently not only ceramide but also sphingosine-1-phosphate (S1P), sphingomyelin (SM) and ceramide-1-phosphate are being app

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Sphingolipids as Mediators of Breast Cancer Progression, Metastasis, Response and Resistance to Chem has been put into developing a thorough understanding of the molecular and genetic events that contribute to tumor progression due to mounting evidence that breast cancers are driven by predictable and identifiable genetic mutations, Sphingolipids modulate many of the growth, apoptosis, inflammator

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Role of Sphingolipids in Non-melanoma Skin Cancerarcinoma (BCC) and squamous cell carcinoma (SCC), both of which arise from malignant keratinocytes, the major cell type in the epidermis of the skin. Most cases of NMSC can be cured by existing new surgical techniques and chemo- or radiotherapy. However, NMSC remains a leading cause of cancer-relate

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Dietary Sphingolipids in Colon Cancer Preventioner day. In the intestinal tract, they are digested to the bioactive metabolites ceramide and free sphingoid bases. These metabolites regulate proliferation, survival and cell death, alter gene expression levels and modulate functions such as angiogenesis, migration and invasion. They also impact loc

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