Titlebook: Bio-Nanomedicine for Cancer Therapy; Flavia Fontana,Hélder A. Santos Book 2021 The Editor(s) (if applicable) and The Author(s), under excl

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Bergtod eines verdienten Mitarbeiters,al genomic depletion would turn the normal tropism of viruses to conditionally replicate in cancer cells only. This category of viruses, named ‘Oncolytic viruses’, have been investigated and used for cancer treatment in the past decades resulting in the approval of the first oncolytic virus, a herpe

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Boosting Nanomedicine Efficacy with Hyperbaric Oxygen Therapynew research hotspot. While a great deal of progress has been made in this direction and preclinical results report many different kinds of promising multifunctional smart nanomedicine, the design of these intelligent nanomedicines is often too complicated, the requirements for the preparation proce

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Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worldssite. Moreover, cancer cell membranes serve as sources of neoantigens, useful in the formulation of nanovaccines. In this chapter, we will discuss the advantages of biohybrid nanosystems in cancer chemotherapy, immunotherapy, and combined therapy, as well as highlight their preparation methods and c

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Nanoneedle-Based Materials for Intracellular Studiesnsors can detect individual vesicles inside the cytoplasm, delineate tumor margins based on intracellular enzyme activity, and measure changes in cell metabolism almost in real time. While most of these applications are currently in the proof-of-concept stage, nanoneedle technology is poised to offe

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3D Tumor Spheroid Models for In Vitro Therapeutic Screening of Nanoparticlesfferences or the interaction between several cell populations may contribute to different tumor response to the treatment. Also, different types of nanoparticles may have different behavior in 3D models, depending on their nature, physicochemical properties, the presence of targeting ligands on the

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Nanotechnology for the Development of Nanovaccines in Cancer Immunotherapygradation, sustain and control the release for the entrapped cargo, and enhance the immune responses..Several studies reported that different physical characteristics of nanoparticles affect their uptake in cells and the potential to induce cellular responses. Among them, particle size and surface c