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Titlebook: Bile Acids in Health and Disease; Update on Cholestero Tim Northfield,Riadh Jazrawi,Patrick Zentler-Munro Book 1988 Kluwer Academic Publish

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期刊全稱Bile Acids in Health and Disease
期刊簡稱Update on Cholestero
影響因子2023Tim Northfield,Riadh Jazrawi,Patrick Zentler-Munro
視頻videohttp://file.papertrans.cn/187/186223/186223.mp4
圖書封面Titlebook: Bile Acids in Health and Disease; Update on Cholestero Tim Northfield,Riadh Jazrawi,Patrick Zentler-Munro Book 1988 Kluwer Academic Publish
影響因子Bile acids occupy a central position in in the absorption, excretion and metab- olism of lipids within the body. Our understanding of their unique properties has illuminated many biochemical and biophysical processes. Animals have evolved a unique system of preserving these important detergent-like molecules within the body and reusing them many times - the enterohepatic circulation. Disorders of the enterohepatic circulation contribute to a correspondingly wide range of diseases, and recent developments have centred in particular on cholesterol gallstone disease and bile acid diarrhoea. Successful manage- ment of these diseases is increasingly based on an understanding of the physicochemical and biochemical properties of bile acids, and of their pathophysiological role in disease. Professor Alan Hofmann starts this book with an overview of the enterohepatic circulation of bile acids. The first section then discusses biliary lipid synthesis, transport and secretion by the liver and the solubilisation of cholesterol in the bile. The next section applies this knowledge to the pathogenesis of cholesterol gallstones. Separate chapters focus on defects in biliary lipid secretion, in cho
Pindex Book 1988
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Hepatic Biliary Lipid Synthesis and Transportnsidering the possible biochemical defects in this system which occur in cholesterol gallstone disease it is therefore worth reviewing, briefly, the structure and function of the hepatocyte in relation to lipid metabolism and its control.
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Hepatic Bile Acid Transport and Secretion glycine, before secretion. The purpose of this review is to examine the cellular mechanisms of bile acid transport by the liver, with particular emphasis on intracellular transport, the step which is at present least well understood.
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The Motility Defectfocus for stone formation. A few years earlier, the simple concept that stasis of gallbladder contents might contribute to the development of gallstones was formulated. The historical development of the role of the gallbladder in gallstone pathogenesis is discussed by LaMorte ... in a valuable but outdated review.
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unique properties has illuminated many biochemical and biophysical processes. Animals have evolved a unique system of preserving these important detergent-like molecules within the body and reusing them many times - the enterohepatic circulation. Disorders of the enterohepatic circulation contribute
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Instrumentation and Experimental Techniques,oss of time from the work force have an important impact on the national economy. Many patients fear general anaesthesia and major abdominal surgery, and may find postoperative disability for several weeks an inconvenient and expensive detraction from their vocation.
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