Titlebook: Beta-Lactam Resistance in Gram-Negative Bacteria; Threats and Challeng Mohammad Shahid,Anuradha Singh,Hiba Sami Book 2022 The Editor(s) (if

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An Overview on Antibiotic Resistance in Gram-Negative Bacteria antibiotics, viz. modification of target site of antibiotics, modification of penicillin binding proteins, permeability-based resistance, and efflux pump, are also described briefly. This chapter will describe various mechanisms of bacteria which are responsible for dissemination of antibiotic resistance among bacterial population.

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The Returns Directive: Normalising Changem, beta-lactamases are classified into Class A, B, C, and D. This chapter will describe class A type beta-lactamases. The most common types of class A ESBLs disseminated worldwide are CTX-M, TEM, and SHV. This chapter will provide significant information regarding nomenclature and variants of class A type beta-lactamases.

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Bridget Jari,Gavin Fraser,Ajuruchukwu ObiTn9, Tn10, Tn903, Tn1525, and Tn2350. Most studied Tn21 bear determinants of OXA (a carbapenem, possessing oxacillinase activity) and PSE (β-lactam gene . specific enzyme) PSE (. unique enzyme-lactam gene) makes them resistant to aminoglycoside antibiotics.

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