Titlebook: Best Practices of Apheresis in Hematopoietic Cell Transplantation; Syed A. Abutalib,Anand Padmanabhan,Nina Worel Book 2020 Springer Nature

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Hongying Lin,Karsten Lindner,Georg W. Mayron regimens. As the most robust predictive factor for poor CD34. cell collection is the CD34. cell count in the peripheral blood before initiation of apheresis, a defined threshold helps to identify patients at risk and allows preemptive intervention to immediate rescue mobilization in these patient

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Mabel Hokin-Neaverson,Gregory S. Parriesonors must undergo hematopoietic progenitor cells mobilization prior to collection. Hematopoietic progenitor cells mobilization in healthy donors is performed utilizing cytokines exclusively. Even among healthy donors, approximately 2–6% do not collect a minimum of 2 × 10. CD34. cells/kg body weight

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https://doi.org/10.1007/978-1-4612-5184-2when evaluating and implementing the use of these devices. In addition, as with any complex medical device, the potential exists for instrument/process failure, in this case inadequate HPC(A) or TC content or the presence of cells in the product which are not desired. In many cases, such failures ar

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Experimental Biology and Medicineagents or density gradient centrifugation with density gradient reagents to optimize processing results. These substances bear a potential risk for the BM cells and the recipients. In the beginning of the 1990s, apheresis technology was substantially improved. The latest innovations in this field we

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Jan-Bj?rn Osnes,H. Aass,T. Skomedaled mortality (TRM). The therapeutic action of ECP in steroid-dependent and steroid-refractory chronic GvHD has been demonstrated by a large body of clinical data including a prospective randomized trial. Steroid-sparing effect is a key feature of this therapeutic modality. Future perspectives of ECP

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Yann Desfougères,Adolfo Saiardi Many regulations and accreditations exist for this process with whom apheresis facilities should be familiar. The chapter provides an overview of the most important regulatory aspects of Apheresis Collection Facilities and a framework of how to become familiar with them.