| 期刊全稱 | Behavioral Neuroscience of Drug Addiction | | 影響因子2023 | David W. Self,Julie K.‘Staley Gottschalk | | 視頻video | http://file.papertrans.cn/183/182871/182871.mp4 | | 發(fā)行地址 | Includes supplementary material: | | 學(xué)科分類 | Current Topics in Behavioral Neurosciences | | 圖書封面 |  | | 影響因子 | Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioratio | | Pindex | Book 2010 |
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