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Titlebook: Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma; Juan Pedro Martinez-Barbera,Cynthia Lilian Andonia Book 2017 Sp

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41#
發(fā)表于 2025-3-28 16:00:38 | 只看該作者
Pathogenesis of Human ACP,a result, controversy than does the craniopharyngioma”. This statement clarifies the situation of medical specialists such as endocrinologists, neurosurgeons, neuropathologists, neurooncologists, paediatric oncologists and neuro-radiologists involved in treatment of craniopharyngioma (CP) patients.
42#
發(fā)表于 2025-3-28 22:33:52 | 只看該作者
Transcriptomic and Genomic Analyses of Human Craniopharyngioma,. Genomic studies of adamantinomatous craniopharyngioma (ACP) have revealed mutations in the . gene, resulting in nuclear and cytoplasmic accumulation of β-catenin protein. Papillary craniopharyngioma (PCP), however, is characterised by the BRAF V600E mutation, which suggests novel therapeutic strat
43#
發(fā)表于 2025-3-29 01:00:30 | 只看該作者
44#
發(fā)表于 2025-3-29 03:11:09 | 只看該作者
Clinical Diagnosis of Human ACP, intracranial tumours in children. The adamantinomatous histological subtype is the most common and the majority of them (94–95%) have a suprasellar component. Their potential proximity to, and the subsequent pressure effects on vital structures of the brain (visual pathways, brain parenchyma, ventr
45#
發(fā)表于 2025-3-29 10:42:23 | 只看該作者
Endocrine Deficits in Patients with Human Craniopharyngioma,from tumour- and treatment-related effects. Endocrine deficits are frequently present at diagnosis but are often under-recognised; thus a detailed pre-treatment endocrine assessment is essential, particularly to exclude adrenocorticotrophic hormone deficiency and central diabetes insipidus prior to
46#
發(fā)表于 2025-3-29 12:31:36 | 只看該作者
Obesity and Metabolic Disturbances in Adamantinomatous Craniopharyngioma Patients, rate in CP is high and therapy of choice is surgery, followed by cranial radiotherapy (CRT) in about half of the patients. Patients with CP have a 3–19 fold higher cardiovascular mortality in comparison to the general population. The majority of patients have an extended hypopituitarism that needs
47#
發(fā)表于 2025-3-29 16:08:45 | 只看該作者
48#
發(fā)表于 2025-3-29 23:02:43 | 只看該作者
Surgical Treatment of Human ACP,y pressure and distortion of the optic nerves and chiasm, the hypothalamus and the pituitary gland. Involvement of the third ventricle causes hydrocephalus. Initial management is surgical and directed towards preservation of vision and control of raised intracranial pressure. Further surgical manage
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