| 期刊全稱 | Base Excision Repair Pathway | | 期刊簡稱 | Methods and Protocol | | 影響因子2023 | Kishor K. Bhakat,Tapas K. Hazra | | 視頻video | http://file.papertrans.cn/181/180910/180910.mp4 | | 發(fā)行地址 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | | 學(xué)科分類 | Methods in Molecular Biology | | 圖書封面 |  | | 影響因子 | This detailed volume provides a comprehensive set of experimental protocols and useful strategies to examine the repair of damaged bases via the Base Excision Repair (BER) pathway .in vitro. and in cells. Beginning with multiple molecular and cellular techniques to examine the excision of damaged bases from double-stranded DNA or DNA wrapped in a nucleosome, the book continues with sections covering procedures to detect and quantify the damaged bases, protein DNA crosslinks, and double-strand breaks, experimental procedures to identify DNA repair protein interactome by conventional tandem affinity purification followed by mass spectroscopy analysis, as well as the analysis of genome-wide binding of DNA repair?proteins?and copy number variations of the DNA damage response gene in tumors. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.?.Authoritative and practical, .Base Excision Repair Pathway: Methods and Protocols. serves as a valuable r | | Pindex | Book 2023 |
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