Titlebook: Autophagy at the Cell, Tissue and Organismal Level; Eleftherios Karanasios,Nicholas T. Ktistakis Book 2016 The Author(s) 2016 Autophagosom

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Signalling in Autophagy,phagic response, but a real breakthrough was achieved with the identification of the mTOR pathway as the master regulator of autophagy. In recent years many more signalling cascades have been shown to regulate autophagy. This chapter will provide an up to date summary of this topic.

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Book 2016health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneratio

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2625-3534 d researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms..978-3-319-33143-0978-3-319-33145-4Series ISSN 2625-3534 Series E-ISSN 2625-3542

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Autophagy at the Cell, Tissue and Organismal Level

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Signalling in Autophagy,ealized in early work that various pharmacological compounds targeting kinase and phosphatase cascades affected the duration and magnitude of the autophagic response, but a real breakthrough was achieved with the identification of the mTOR pathway as the master regulator of autophagy. In recent year

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Eleftherios Karanasios,Nicholas T. KtistakisCovers autophagy from the basic mechanisms to its effects at the cell, tissue and organism level.Includes an extensive list of antibodies for the study of autophagy.Written by experts in the field.Inc