| 期刊全稱 | Autoimmunity | | 期刊簡稱 | Methods and Protocol | | 影響因子2023 | Andras Perl | | 視頻video | http://file.papertrans.cn/167/166158/166158.mp4 | | 發(fā)行地址 | Includes supplementary material: | | 學(xué)科分類 | Methods in Molecular Medicine | | 圖書封面 |  | | 影響因子 | “Research is to see what everybody else has seen, and to think what nobody else has thought. ” — Albert Szentgy?rgyi Autoimmunity: Methods and Protocols is intended to serve as a ready-to-use guide to establish and interrogate human and animal models of autoimmune diseases. The first chapter, “Pathogenesis and Spectrum of Autoimmunity,” discusses major hypotheses driving this most tantalizing area of research since Paul Ehrlich proposed the concept of autoimmunity in 1900. Considering the great diversity and ever-changing spectrum of autoimmunity, it has not been possible to include models and experimental protocols for each known disorder. Rather, several chapters have been devoted to the most prevalent and complex diseases, such as rheumatoid arthritis, systemic lupus erythematosus, insulin-dependent diabetes mellitus, and multiple sclerosis. The chapters are contributed by laboratories actively using the models presented. Each chapter contains an introductory section that discusses the relevance of the model for a particular disease and for autoimmunity in general. Part I contains methods and protocols to assess immunological and biochemical pathways relevant for disease pathoge | | Pindex | Book 20041st edition |
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