Titlebook: Assessment of Mammalian Embryo Quality; Invasive and non-inv Ann Soom,Marleen Boerjan Book 2002 Springer Science+Business Media Dordrecht 2

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Michael J. Shkrum,David A. Ramsayentesis between 8 and 20 weeks of gestation, prior to cytogenetic, biochemical or molecular analysis. If the foetus is diagnosed as affected, therapeutic termination can be offered. The accessibility of preimplantation embryos following IVF has raised the possibility of preimplantation diagnosis. Th

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https://doi.org/10.1007/978-1-59745-138-3ion and flushing of the uterus at day 7 after insemination. Alternatively, in vitro grown embryos can be generated from immature oocytes after in vitro maturation, fertilization and culture for 7 days. The selection of transferable embryos is generally based on the morphology and their expected bree

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https://doi.org/10.1007/978-1-59745-138-3jor, criterion for assessing embryo quality in both human and domestic animal reproductive fields. Microscopy has been an important tool for improving our ability to observe and investigate mammalian embryo development. Much has been learned by electron microscopy (Stern et al., 1971; Longo, 1973; P

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Michael J. Shkrum,David A. Ramsayian or mammalian embryo shows many similarities between different species. The fertilized mammalian oocyte follows a common pattern of cleavage divisions, compaction and blastulation. Furthermore, the initial size of the embryo does not vary greatly between species. It is therefore difficult for an

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https://doi.org/10.1007/978-1-59745-138-3l limit in order to assess the nature of structures that escape the resolution of the equipment. However, non-invasive microscopical techniques for embryo evaluation are hampered by on the one hand, the limit of resolution of the stereo microscope normally working within magnifications up to a few h

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https://doi.org/10.1007/978-1-59745-138-3logical changes such as compaction, cavitation and blastocoel formation. These rapid changes in morphology require the well-orchestrated expression of developmentally important genes expressed from the maternal and/or embryonic genome (Kidder, 1992). The early stages of mammalian preimplantation dev

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