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Titlebook: Aspergillus and Aspergillosis; Hugo Bossche,Donald W. R. Mackenzie,Geert Cauwenbe Book 1988 Springer Science+Business Media New York 1988

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發(fā)表于 2025-3-21 16:42:33 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Aspergillus and Aspergillosis
影響因子2023Hugo Bossche,Donald W. R. Mackenzie,Geert Cauwenbe
視頻videohttp://file.papertrans.cn/164/163168/163168.mp4
圖書封面Titlebook: Aspergillus and Aspergillosis;  Hugo Bossche,Donald W. R. Mackenzie,Geert Cauwenbe Book 1988 Springer Science+Business Media New York 1988
影響因子Species of aspergilli are common in man‘s environment and are responsible for a wide spectrum of human and animal disease, ranging in animals from mycotic abortion to aflatoxicosis and in humans from localized colonization of the ear or skin to life-threatening systemic infection of neutropenic patients. In recent times, invasive aspergillosis has become increasingly important as a cause of morbidity and death, initially in patients receiving immunosuppression prior to organ transplantation, and latterly in haematologic patients rendered neutropenic by underlying disease or chemotherapy. In some centres, the condition has been recorded in more than 40% of patients dying with acute leukaemia. Laboratory diagnostic procedures are not always helpful and the diagnosis depends largely on clinical parameters. The clinician is faced with yet another problem, that of management. At present, antifungal therapy of invasive aspergillosis can be largely ineffectual, and the mortality rate remains unacceptably high. Since Aspergillus fumigatus was first described almost 125 years ago, several other pathogenic species have been recognized. The marked biosynthetic abilities and varied mechanisms
Pindex Book 1988
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書目名稱Aspergillus and Aspergillosis影響因子(影響力)




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發(fā)表于 2025-3-21 21:55:56 | 只看該作者
Epidemiology of Aspergillosisf bacterial nature as the main cause of certain infectious diseases, he nevertheless described in the last year of his academic position as Professor of Pathology at the Medical Faculty of the University of Würzburg human aspergillosis in a beautifully illustrated paper as a mycotic airborne infecti
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發(fā)表于 2025-3-22 03:56:07 | 只看該作者
Ecology of Aspergillus Species in the Human Environmentas been demonstrated in such divers sources as soil, decaying vegetation, air and even water. In addition it is a commonly cultured mold from houses and is especially found in basements, crawl spaces, bedding and house dust.
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發(fā)表于 2025-3-22 05:03:35 | 只看該作者
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發(fā)表于 2025-3-22 11:56:07 | 只看該作者
Pulmonary Aspergillosis — The Clinical Spectrumally mediated (allergic) disease to frank invasion of the lung parenchyma (Bardana, 1981). An understanding of the pathogenic mechanisms is fundamental to any discussion of the clinical spectrum of disease states. There are three main processes involved in the interaction between aspergilli and the
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發(fā)表于 2025-3-22 14:02:58 | 只看該作者
Role of the Phagocyte in Host Defense against Aspergillosisis infection in 40 of 245 patients with chronic granulomatous disease is a strong indication that impaired oxidative killing of . by human phagocytes put these patients at increased risk (Cohen et al., 1981). Patients with acute leukemia and prolonged granulocytopenia have also been shown to be at i
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發(fā)表于 2025-3-22 20:55:38 | 只看該作者
Host Tissue Responses to Pathogenic and Non-Pathogenic Fungi, Including Aspergilli have not been adequately elucidated. Since the use of corticosteroids and immunosuppresives, opportunistic infections by fungi have increased, though information on the pathogenicity of fungi and host defence mechanisms remains largely incomplete. The present report may contribute to a better under
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發(fā)表于 2025-3-23 02:48:06 | 只看該作者
Sterol Metabolism in , Speciesol molecule, such as cholesterol (in animals), sitosterol (in plants), and ergosterol (in fungi). These neutral lipid molecules act not only as a bulk lipid, but also act to stabilize the fluidity of the membrane structure, thus allowing for protein function under conditions such as high or low temp
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發(fā)表于 2025-3-23 06:48:12 | 只看該作者
Polyene Macrolide Antibioticsom topical fungal infections. Since then, some 200 polyenes have been isolated and about forty characterised chemically: four or five are in current clinical use. During this period there have been significant advances in the development of other antifungal compounds, in particular 5-fluorocytosine,
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