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Titlebook: Articular Cartilage Tissue Engineering; Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu Book 2010 Springer Nature Switzerland AG 2010

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發(fā)表于 2025-3-21 16:32:01 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Articular Cartilage Tissue Engineering
影響因子2023Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu
視頻videohttp://file.papertrans.cn/162/161979/161979.mp4
學科分類Synthesis Lectures on Tissue Engineering
圖書封面Titlebook: Articular Cartilage Tissue Engineering;  Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu Book 2010 Springer Nature Switzerland AG 2010
影響因子Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage‘s low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analys
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Cartilage Aging and Pathology: The Impetus for Tissue Engineering,ation can last for years before the mechanically inferior repair tissue degenerates to result in significant pain and even disability. What is clear is that long-lasting functional restoration is naturally absent, and, if one judges “healing” by this criterion, then cartilage is devoid of a complete healing response.
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Bioreactors,due to the variety of cell sources, media cocktails, and general laboratory practices used from study to study. In general, cell-seeded scaffolds, or “constructs,” are cultured . to help produce a neo-tissue that has sufficient mechanical and/or biochemical properties for implantation.
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