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Titlebook: Arenaviruses; Biology and Immunoth Michael B. A. Oldstone Conference proceedings 1987 The Editor(s) (if applicable) and The Author(s), unde

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發(fā)表于 2025-3-21 19:21:23 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Arenaviruses
期刊簡稱Biology and Immunoth
影響因子2023Michael B. A. Oldstone
視頻videohttp://file.papertrans.cn/162/161494/161494.mp4
學科分類Current Topics in Microbiology and Immunology
圖書封面Titlebook: Arenaviruses; Biology and Immunoth Michael B. A. Oldstone Conference proceedings 1987 The Editor(s) (if applicable) and The Author(s), unde
影響因子M. B. A. OLDSTONE Viruses are generally studied either because they cause significant human, animal or plant disease or for their utility as materials to probe a basic phenomenon in biology, chemistry, genetics or molecular biology. Arenaviruses are unusually interesting in that they occupy both of these categories. Arenaviruses cause severe human diseases known primarily as the hemor- rhagic fevers occurring in South and Latin America (Bolivia: Machupo virus and Argentina: Junin virus) and in Africa (Lassa virus). Because such viruses produce profound disability and may kill the persons they infect, they are a source of economic hardship in the countries where they are prevalent. Further, they provide new problems for health care personnel owing to the narrowing of the world as visitors from many countries increasingly travel to and from these endemic areas. In addition, lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling than those elicited by other arenaviruses. Yet LCMV is likely of greater concern to non-arena-virologists and experimentalists using tissue culture or animals, i. e. , workers in molecular biolo
Pindex Conference proceedings 1987
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發(fā)表于 2025-3-21 22:10:48 | 只看該作者
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Argentine Hemorrhagic Fever, heart of the richest farmlands of Argentina. Unknown before the 1950s, its salient clinical features are hematologic and neurologic signs, including a febrile syndrome, together with varying degrees of cardiovascular, renal, and digestive alterations, first described in detail in 1955 (. 1955).
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Clearance of Virus by T Lymphocytes Mediating Delayed Type Hypersensitivity,lly and prophylactically. to overcome human disease caused by infectious agents. Not surprisingly, at present such experimentation focuses considerably on viruses, since these agents do not to any noteworthy degree respond to antibiotics or chemotherapy. In spite of this research, however, it is sti
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發(fā)表于 2025-3-22 16:14:58 | 只看該作者
Regulation and Role of Large Granular Lymphocytes in Arenavirus Infections,r LGL (. and . 1980). The granules appear to contain cytotoxic substances that are released upon binding of effector cell to target cell (. et al. 1981). These attach to the membrane of the target cell, and, by uncertain mechanisms, induce lysis of the target (. et al. 1984; . and . 1983; . et al. 1
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發(fā)表于 2025-3-22 20:25:50 | 只看該作者
Immunotherapy for Virus Infection,at suppression of immune responses changed the ordinarily lethal, acute infection with lymphocytic choriomeningitis virus (LCMV) to a persistent infection in susceptible mice. The subsequent work of many investigators who used neonatal thymectomy, genetically athymic mice, irradiation, antilymphoid
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發(fā)表于 2025-3-23 00:42:11 | 只看該作者
Pathophysiology and Treatment of Lassa Fever,rom an uncomplicated fever of unknown origin to a fulminating hemorrhagic disease. Following an incubation period of 7–14 days, onset is typically insidious. As the disease progresses, patients usually develop pharyngitis, which is often purulent and accompanied by headache, fever, myalgia, back or
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發(fā)表于 2025-3-23 01:55:34 | 只看該作者
Argentine Hemorrhagic Fever, heart of the richest farmlands of Argentina. Unknown before the 1950s, its salient clinical features are hematologic and neurologic signs, including a febrile syndrome, together with varying degrees of cardiovascular, renal, and digestive alterations, first described in detail in 1955 (. 1955).
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發(fā)表于 2025-3-23 05:47:48 | 只看該作者
Research by design on agroparks,Lymphocytic choriomeningitis (LCM) is an inflammatory disease that occurs in immunologically competent adult mice after infection of the brain with LCM virus (LCMV). Tremors develop in the legs, head, and tail, and characteristic extensor spasms of the hind legs are found during the terminal stage of disease, usually within 1 week of infection.
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