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Titlebook: Applied Statistics in Biomedicine and Clinical Trials Design; Selected Papers from Zhen Chen,Aiyi Liu,Yi Tsong Conference proceedings 2015

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發(fā)表于 2025-3-25 07:17:02 | 只看該作者
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Derivation of Mathematical Models,bability for observing a sufficient magnitude of response rate at the end of enriched enrollment phase given the observed data at an interim look. The method is applied to derive futility stopping rules, and the sensitivity of the futility stopping rules is examined based upon the choice of prior di
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發(fā)表于 2025-3-25 20:06:18 | 只看該作者
Enzyme Kinetics of PAPS-Sulfotransferasernative hypotheses for both plausible endpoints. Here, we explore characteristics of the design when the alternative hypothesis for only one of the two endpoints is true, and the treatment effect for another endpoint is null (an extremely worst case) or lower than what was anticipated per trial desi
26#
發(fā)表于 2025-3-26 02:57:27 | 只看該作者
Jaydeep Yadav,Ken Korzekwa,Swati Nagarility of study success (PrSS) or probability of success (POS). We discuss the important role that PrSS can play in clinical trial design and decision making throughout medical product development. A few examples are given for illustration.
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