Titlebook: Applied Computational Genomics; Yin Yao Shugart Book 2012 Springer Science+Business Media Dordrecht 2012 Gene mapping.exon sequencing.link

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QTL Mapping of Molecular Traits for Studies of Human Complex Diseases,ine novel functional implications of genetic variants. Here we reviewed recent progress on QTL mapping of molecular traits, including gene expression, DNA methylation, as well as protein expression, metabolites. QTL mapping of molecular traits has better chance to succeed in relatively small sample

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Analytical Approaches for Exome Sequence Data,rlying Mendelian disease. It is possible that exome sequencing in a relatively small number of individuals showing ‘extreme’ phenotypes or more familial subtypes of complex disease may also be productive. Larger-scale exome and whole genome sequencing studies offer the potential to interrogate the c

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Rare Variants Analysis in Unrelated Individuals,e genetic architecture of human diseases, their limitation of explaining the missing heritability motivated researchers to test the hypothesis that rare variants contribute to the variation of common diseases, that is, common disease/rare variants (CDRV) hypothesis. The fast developed high-throughpu

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浮雕寶石