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Titlebook: Application of Monoclonal Antibodies in Tumor Pathology; Dirk J. Ruiter,Gert Jan Fleuren,Sven O. Warnaar Book 1987 Springer Science+Busine

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期刊全稱Application of Monoclonal Antibodies in Tumor Pathology
影響因子2023Dirk J. Ruiter,Gert Jan Fleuren,Sven O. Warnaar
視頻videohttp://file.papertrans.cn/160/159151/159151.mp4
學(xué)科分類Developments in Oncology
圖書封面Titlebook: Application of Monoclonal Antibodies in Tumor Pathology;  Dirk J. Ruiter,Gert Jan Fleuren,Sven O. Warnaar Book 1987 Springer Science+Busine
影響因子The development of monoclonal antibodies to human tumor associated antigens has greatly facilitated the application of immunohistochemical techniques to analyze surgically removed tissues. During the last few years this approach has been utilized by a progressively increasing number of investigators to analyze malignant cells. Although monoclonal antibodies to tumor associated antigens have not become yet routine reagents in immunopathology, they have provided new information which could not be obtained with conventional antisera or histochemical procedures. The following are representative examples. TUmor associated antigens have been identified which display a restricted distribution in normal tissues and therefore may represent useful markers for radio- imaging and appropriate targets for immunotherapy. In spite of undetec- table differences with conventional histopathological approaches hetero- geneity has been found in the antigenic profile of tumor cells within a lesion, in autologous lesions removed from different anatomic sites from a given patient and in lesions removed from different patients. Phenotypes of tumor cells have been identified which correlate with the biology
Pindex Book 1987
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Cytoskeletal Proteins as Markers in Surgical Pathology.al composition. Next to microfilaments and microtubules, filaments measuring 8–11 nm in diameter are commonly seen in mammalian cells. These so-called intermediate-sized filaments, which often constitute a considerable part of the intracellular matrix (Figure 1), are extremely insoluble and show a p
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Immunological marker analysis of cells in the various hematopoietic differentiation stages and theirained by immunological marker analysis (1–4). The expression of a particular set of immunological markers designates a cell to a particular differentiation stage. The various markers are detectable by means of antibodies or by rosette techniques (5–7).
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Monoclonal Antibodies in Lymphoma Diagnosis and Classification.sis and a more precise subclassification of malignant lymphomas. The wide application of monoclonal antibodies on frozen tissue sections makes one almost forget that the first monoclonal anti T cell reagents were described in 1979 (1), and the first applications of such antibodies on human lymph nod
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Monoclonal Antibodies Reacting with Tumors of the Urological Tract or Prostateical manifestations. Also the variable aspects of cell morphology, such as clear cells, spindle cells and solid undifferentiated cells can lead to diagnostic problems in metastatic RCC, although in large sections the presence of all cell types mentioned above usually permits unequivocal identificati
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