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Titlebook: Antiplatelet Agents; Paolo Gresele,Gustav V. R Born,Clive P. Page Book 2012 Springer-Verlag Berlin Heidelberg 2012 Antithrombotic Therapy.

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發(fā)表于 2025-3-21 18:08:55 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Antiplatelet Agents
影響因子2023Paolo Gresele,Gustav V. R Born,Clive P. Page
視頻videohttp://file.papertrans.cn/159/158648/158648.mp4
發(fā)行地址Written by leading experts in the field.With numerous illustrations.Gives an overview on the current state of the art.Includes supplementary material:
學科分類Handbook of Experimental Pharmacology
圖書封面Titlebook: Antiplatelet Agents;  Paolo Gresele,Gustav V. R Born,Clive P. Page Book 2012 Springer-Verlag Berlin Heidelberg 2012 Antithrombotic Therapy.
影響因子Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A large group of leading experts from different European countries and from the USA, both from academia and industry, have contributed to the book. Besides a detailed overview on the pharmacology and clinical applications of all the currently used or of the novel antiplatelet agents, innovative approaches (e.g. intracellular signalling as an antiplatelet target, small RNAs as platelet therapeutics, etc.) or unconventional aspects (e.g. pharmacologic modulation of the inflammatory action of platelets are also treated. The book is oriented to both basic investigators and to clinicians involved with research on platelet inhibition or with the clinical use of antiplatelet therapies.
Pindex Book 2012
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發(fā)表于 2025-3-21 22:03:08 | 只看該作者
Platelets: Production, Morphology and Ultrastructuresmic reticulum that form the dense tubular system (DTS); a spectrin-based membrane skeleton; an actin-based cytoskeletal network; a peripheral band of microtubules; and numerous organelles including α-granules, dense-granules, peroxisomes, lysosomes, and mitochondria. Proplatelet elongation and plat
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Inhibitors of the Interactions Between Collagen and Its Receptors on Plateletstors have a good antithrombotic effect, with little prolongation of bleeding times, suggesting a larger therapeutic window than currently available antiplatelet drugs. However, at present, none of the collagen receptor blockers are in clinical development yet.
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發(fā)表于 2025-3-23 09:33:21 | 只看該作者
Small RNAs as Potential Platelet Therapeuticscell gene therapy to the desired lineage, including megakaryocytes and platelets. Finally, manipulation of gene expression in stored platelets may allow more effective platelet storage. Although much work remains to be done, there is great potential in miRNA-based platelet therapies.
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