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Titlebook: Antimicrobial Peptides; Basics for Clinical Katsumi Matsuzaki Book 2019 Springer Nature Singapore Pte Ltd. 2019 Mechanism of action.Antise

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發(fā)表于 2025-3-21 17:59:14 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Antimicrobial Peptides
期刊簡(jiǎn)稱Basics for Clinical
影響因子2023Katsumi Matsuzaki
視頻videohttp://file.papertrans.cn/159/158604/158604.mp4
發(fā)行地址Presents the latest findings on antimicrobial peptides.Elucidates their mechanisms of antimicrobial action.Examines AMP activities beyond antimicrobial action.Discusses the progress made, and obstacle
學(xué)科分類Advances in Experimental Medicine and Biology
圖書封面Titlebook: Antimicrobial Peptides; Basics for Clinical  Katsumi Matsuzaki Book 2019 Springer Nature Singapore Pte Ltd. 2019 Mechanism of action.Antise
影響因子.This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seek
Pindex Book 2019
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發(fā)表于 2025-3-21 21:16:21 | 只看該作者
Membrane Permeabilization Mechanismsding to membranes; various mechanisms of lipid bilayer permeabilization including the barrel-stave, toroidal pore, and carpet models; and modes of permeabilization of bacterial and mammalian membranes.
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The Mechanisms of Action of Cationic Antimicrobial Peptides Refined by Novel Concepts from Biophysic surprises and add new interesting detail to how these peptides exert their antimicrobial action. Early on, using oriented solid-state NMR spectroscopy, it was found that the amphipathic helices formed by magainins are active when being oriented parallel to the membrane surface. More recent investig
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Intracellular Antimicrobial Peptides Targeting the Protein Synthesis Machineryill being elucidated. In the recent years, it has been demonstrated that the subclass of proline-rich AMPs (PrAMPs) can pass through the bacterial membrane and kill bacteria by inhibiting protein synthesis. PrAMPs are a product of the innate immune system and are secreted in response to bacterial in
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Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospectsresolution of infections. CHDPs are expressed across diverse species, are generally amphipathic with less than 50 amino acids in length, and differ significantly in sequence and structure. This chapter focuses on the role of these peptides in immunity. CHDPs are known to function in both innate and
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