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Titlebook: Anticancer Drug Discovery and Development: Natural Products and New Molecular Models; Proceedings of the S Frederick A. Valeriote,Thomas H.

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21#
發(fā)表于 2025-3-25 05:50:29 | 只看該作者
22#
發(fā)表于 2025-3-25 10:33:14 | 只看該作者
https://doi.org/10.1007/978-3-662-38422-0 daily oral administration of “Nolvadex” (1,2). In view of this experience, it is reasonable to question whether there is either a clinical need, or pharmacological rationale, for novel antiestrogens. In our review of these questions, the answer was affirmative in both respects and led to the definition of a new drug target.
23#
發(fā)表于 2025-3-25 13:48:27 | 只看該作者
24#
發(fā)表于 2025-3-25 17:49:21 | 只看該作者
Discovery of Natural Products from Microalgae and Marine Organisms,screening or a subsequence of synthesis of analogs of lead drugs (Table 1). Specifically, the discovery of cytotoxic agents from natural sources has had a rich and fruitful past with the identification of agents such as vincristine and taxol from plants and a number of antibiotics such as adriamycin from fermentations.
25#
發(fā)表于 2025-3-25 21:22:15 | 只看該作者
The Therapeutic Potential of Novel Pure Antiestrogens, daily oral administration of “Nolvadex” (1,2). In view of this experience, it is reasonable to question whether there is either a clinical need, or pharmacological rationale, for novel antiestrogens. In our review of these questions, the answer was affirmative in both respects and led to the definition of a new drug target.
26#
發(fā)表于 2025-3-26 00:14:31 | 只看該作者
27#
發(fā)表于 2025-3-26 05:52:10 | 只看該作者
Novel Strategies for the Discovery of Plant-Derived Anticancer Agents,0 species of flowering plants on this planet, of which it is estimated that 155,000 are found in the tropics (1), consequently, a rational strategy for drug discovery is required, since it is unrealistic to believe that all plants can be investigated biologically.
28#
發(fā)表于 2025-3-26 11:50:38 | 只看該作者
29#
發(fā)表于 2025-3-26 13:08:03 | 只看該作者
Microorganisms: Strategic Sources of Novel Antitumor Agents,ound produced by a microorganism which kills or inhibits the growth of other microorganisms in low concentrations”. Now, the definition seems to extend to any bioactive compound produced by microorganisms.
30#
發(fā)表于 2025-3-26 16:58:54 | 只看該作者
Prozessmodell des Rezeptionsmarktes,0 species of flowering plants on this planet, of which it is estimated that 155,000 are found in the tropics (1), consequently, a rational strategy for drug discovery is required, since it is unrealistic to believe that all plants can be investigated biologically.
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