| 期刊全稱 | Antibody Glycosylation | | 影響因子2023 | Marija Pezer | | 視頻video | http://file.papertrans.cn/159/158475/158475.mp4 | | 發(fā)行地址 | Provides a comprehensive overview on biosynthesis, regulation, functionality, analytics, and applications of immunoglobulin glycosylation.Covers automatization and bioinformatics in high-throughput an | | 學(xué)科分類 | Experientia Supplementum | | 圖書封面 |  | | 影響因子 | .This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy..Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengin | | Pindex | Book 2021 |
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