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Titlebook: Antiarrhythmic Drugs; E. M. Vaughan Williams Book 1989 Springer-Verlag Berlin Heidelberg 1989 drug.electrophysiology.pharmacology.physiolo

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發(fā)表于 2025-3-21 19:42:51 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Antiarrhythmic Drugs
影響因子2023E. M. Vaughan Williams
視頻videohttp://file.papertrans.cn/159/158387/158387.mp4
學(xué)科分類Handbook of Experimental Pharmacology
圖書封面Titlebook: Antiarrhythmic Drugs;  E. M. Vaughan Williams Book 1989 Springer-Verlag Berlin Heidelberg 1989 drug.electrophysiology.pharmacology.physiolo
影響因子The development of a new antiarrhythmic drug involves many people with disparate skills. The organic chemist who makes it is guided not only by the structure-action relations of previous compounds, but by anticipation of a requirement for a particular type of action. In fact several of the best-known antiarrhythmics, including lidocaine, mexiletine, amiodarone and verapamil, were originally synthesized for other purposes. Physicians have to determine whether the new drug works, and pharma- cologists how it works. For some years I have believed that there was room for a work which could be understood by all these groups and which could enlighten each about the point of view of the others. Thus when I was invited by Springer-Verlag to prepare a volume in their series Handbook of Experimental Pharmacology, I already had a firm conception of what its form should be. In any multi-author work there are two objectives which cannot always readily be reconciled. The first is to select topics which would relate to each other in a coherent manner. to give a logical and orderly shape to the volume as a whole. The second is to offer authors the greatest possible freedom to express themselves as
Pindex Book 1989
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沙發(fā)
發(fā)表于 2025-3-21 23:21:32 | 只看該作者
978-3-642-73668-1Springer-Verlag Berlin Heidelberg 1989
板凳
發(fā)表于 2025-3-22 03:57:44 | 只看該作者
地板
發(fā)表于 2025-3-22 05:10:10 | 只看該作者
Einführung in die Praktische Physiologiects of antiarrhythmic drugs. A large number of antiarrhythmic agents are available for clinical use. All are of proven efficacy. Yet the question remains: is a particular agent going to benefit a particular patient?
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Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/a/image/158387.jpg
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發(fā)表于 2025-3-23 00:58:58 | 只看該作者
E. O. Wilson,W. H. Bossert,U. Jacobsne of Na, Ca, K and Cl ions, which would be in equilibrium at intracellular potentials of approximately +56, +120, -94 and -40mV respectively. In order that current from these sources may be used for physiological functions, ion- selective pathways through the membrane can be opened and closed. The
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發(fā)表于 2025-3-23 02:19:36 | 只看該作者
https://doi.org/10.1007/978-3-642-92693-8 antiarrhythmic drug action. The number and diversity of experimental animal models used to screen and evaluate potential antiarrhythmic agents points out the inadequacy of any one model to reproduce the malignant arrhythmias which occur in man. An ideal animal model would both closely simulate a hu
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發(fā)表于 2025-3-23 06:43:08 | 只看該作者
,Pharmazeutische T?tigkeiten Theoretisches,ent or therapeutic consequences. Attempts have been made to obtain some consensus for defining and classifying cardiac arrhythmias and conduction disturbances (WHO/ISFC TASK FORCE 1978, 1979). With so many possibilities, any classification may seem to be the best from a particular point of view, wit
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