Titlebook: Antiangiogenic Agents in Cancer Therapy; Beverly A. Teicher Book 19991st edition Springer Science+Business Media New York 1999 angiogenesi

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Intra- and Extracellular pH in Solid Tumorsmay cause hydrolysis of ATP, resulting in the generation of H. ions .. For reasons unknown, small amounts of β-hydrobutyric acid were detected in experimental tumors .. Such overproduction of acidic metabolites, notably lactic acid combined with slow discharge of the acidic metabolites via sluggish

hypotension

Contribution of the Extracellular Matrix and Macrophages in Angiogenesisy of proteolytic enzymes, the ECM is able to regulate the availability of soluble angiogenic mediators to endothelial cells and specify the nature and type of interactions that endothelial cells have with integrins and cellular adhesion molecules . By exerting mechanical forces along the course of d

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Angiostatin Protein and Other Plasminogen Fragments primary tumor growth. By virtue of its longer half-life in circulation, negative regulators circulate to other distal sites and inhibit endothelial cell growth, which in turn causes inhibition of metastatic growth . The hypothesis proposed by O’Reilly and Folkman was validated with the identificati

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https://doi.org/10.1007/978-1-59259-453-5angiogenesis; cancer; cancer treatment; clinical trial; interferon; macrophages; tumor; tumor growth; tumor

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,Empirische Moleküleigenschaften, the earliest descriptions of MMPs was as depolymerizing enzymes, including that of small blood vessels,morefluid ..Sudequent research has shown that these enzymes paly a central role in the tissue remodeling associated with both physiological and pathogenic processes.