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Titlebook: Anti-Idiotypic Vaccines; P.-A. Cazenave Book 1991 Springer-Verlag New York Inc. 1991 Antigen.cell.genes.parasite.parasites.research.vaccin

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發(fā)表于 2025-3-21 18:15:56 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Anti-Idiotypic Vaccines
影響因子2023P.-A. Cazenave
視頻videohttp://file.papertrans.cn/159/158337/158337.mp4
學(xué)科分類Progress in Vaccinology
圖書封面Titlebook: Anti-Idiotypic Vaccines;  P.-A. Cazenave Book 1991 Springer-Verlag New York Inc. 1991 Antigen.cell.genes.parasite.parasites.research.vaccin
影響因子Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine~hat enabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunology and genetic engineering. Vaccines that confer short or inadequate immunity or that have side effects are being replaced by better vaccines. New vaccines are being developed for a variety of maladies. Monoclonal antibodies and T cell clones have been employed to delineate the immunodeterminants on microbes, an approach elegantly complemented by computer graphics and molecular imaging techniques. Possibilities have opened for obtaining hitherto scarce antigens of parasites by the DNA recombinant route. Better appreciation of the idiotypic network has aroused research on anti-idiotypic vaccines. Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the
Pindex Book 1991
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發(fā)表于 2025-3-21 22:46:47 | 只看該作者
Anti-Idiotypic Vaccines for Carbohydrate Antigens,ti-idiotype might behave as an internal image of antigen or Ab2β (1). The criteria I will use to determine whether an anti-idiotype is an internal image are those first discussed with reference to vaccines by Nisonoff and colleagues (2, 3).
板凳
發(fā)表于 2025-3-22 04:10:45 | 只看該作者
0941-875X nabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place
地板
發(fā)表于 2025-3-22 08:10:06 | 只看該作者
https://doi.org/10.1007/978-3-540-74452-8o an idiotypic site cross-reacting with that determinant, and for which we propose the name of homobody. Accordingly, antigenic determinants are projected into the world of immunoglobulin molecules in two manners: as negative images, these define antibodies; as positive images, these define homobodies.
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發(fā)表于 2025-3-22 10:57:41 | 只看該作者
Idiotype Vaccines by Antibody Engineering: Structural and Functional Considerations,o an idiotypic site cross-reacting with that determinant, and for which we propose the name of homobody. Accordingly, antigenic determinants are projected into the world of immunoglobulin molecules in two manners: as negative images, these define antibodies; as positive images, these define homobodies.
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發(fā)表于 2025-3-22 15:57:47 | 只看該作者
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發(fā)表于 2025-3-22 20:07:18 | 只看該作者
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發(fā)表于 2025-3-23 00:31:51 | 只看該作者
Einführung in die Kryptographie this model system we were able to specifically determine the receptor interaction sites by sequence homology with the viral hemagglutinin. Based on these sequences we produced functionally active mimics that interfere with virus binding and maintain, when suitably constructed, many properties of the hemagglutinin.
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發(fā)表于 2025-3-23 01:53:48 | 只看該作者
,Utilization of Anti-Idiotypic Antibodies as Molecular Probes of Virus—Receptor Interaction, this model system we were able to specifically determine the receptor interaction sites by sequence homology with the viral hemagglutinin. Based on these sequences we produced functionally active mimics that interfere with virus binding and maintain, when suitably constructed, many properties of the hemagglutinin.
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發(fā)表于 2025-3-23 07:07:44 | 只看該作者
Book 1991bal eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunol
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