Titlebook: Annual Update in Intensive Care and Emergency Medicine 2022; Jean-Louis Vincent Book 2022 The Editor(s) (if applicable) and The Author(s),

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Hemoadsorption Therapy During ECMO: Emerging Evidencethese patients remains high. Adjunctive therapies have been used with the goal of improving outcomes. Extracorporeal hemoadsorption is an adjunctive therapy that can be easily combined with ECMO. Several devices are available; however, data supporting their use in this setting is limited. Case repor

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The Forgotten Circulation and Transpulmonary Pressure Gradientse gradient). This is the essential pressure that overcomes vascular resistance and is a cornerstone of hemodynamic resuscitation, enabling oxygenation and cardiac output. With advanced critical care echocardiography and possible resurgence in the use of contemporary pulmonary artery catheters, inten

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Nebulized Therapeutics for COVID-19 Pneumonia in Critical Carepneumonia of varying severity resulting in respiratory failure. COVID-19 pneumonia patients require prolonged hospitalization and often critical care support including mechanical ventilation. Despite extensive research, current formulations and dose regimens of systemic therapeutics assessed for use

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Positive End-Expiratory Pressure in Invasive and Non-invasive Ventilation of COVID-19 Acute Respirattress syndrome (ARDS). In the case of ARDS arising due to coronavirus disease 2019 (COVID-19, CARDS), there is some debate as to whether the atypical pathophysiological characteristics of the disease, which lead to hypoxemia could warrant a modified approach to ventilator management, particularly wi

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Personalized Mechanical Ventilation Settings: Slower Is Better!sitive end-expiratory pressure (PEEP)]) and dynamic (respiratory rate, inspiratory, and expiratory peak flow) variables may promote ventilator-induced lung injury (VILI), multiple organ dysfunction, and death. In clinical practice, any of these variables may be set abruptly, thus increasing the risk

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