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Titlebook: Animal Models of Behavior Genetics; Jonathan C. Gewirtz,Yong-Kyu Kim Book 2016 Springer Science+Business Media New York 2016 animal models

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發(fā)表于 2025-3-21 17:15:26 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Animal Models of Behavior Genetics
影響因子2023Jonathan C. Gewirtz,Yong-Kyu Kim
視頻videohttp://file.papertrans.cn/158/157632/157632.mp4
發(fā)行地址Provides source information for behavioral genetics researchers.Written by leading researchers expert in animal behavioral models in behavioral genetics research.Focuses on both function and dysfuncti
學(xué)科分類Advances in Behavior Genetics
圖書封面Titlebook: Animal Models of Behavior Genetics;  Jonathan C. Gewirtz,Yong-Kyu Kim Book 2016 Springer Science+Business Media New York 2016 animal models
影響因子This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The models highlight genetic causes of core features, or endophenotypes, of developmental, internalizing, and externalizing disorders, as well as dementia. Expert contributors address questions ranging from how suitable species are chosen for study to the costs and benefits of using inbred versus outbred strains, and the effects of housing environment on subject animals. Larger issues addressed include how to evaluate the applicability of animal behavioral models to the human condition and how these models can harness emerging molecular technologies to further our understanding of the genetic basis ofmental illness..Included in the coverage:.Mating and fighting in?.Drosophila...Attachment and social bonding..Impulsivity in rodents and humans..Animal models of cognitive decline..Animal models of soc
Pindex Book 2016
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發(fā)表于 2025-3-21 23:18:37 | 只看該作者
A , Model for Aggressiony genes, environment, and interaction between genes and environment. The fruit fly . model system offers the advantage of having powerful genetic tools that can be used to unravel the roles of genes and other factors in behavior. In this chapter, studies of aggressive behavior in . will be reviewed
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發(fā)表于 2025-3-22 03:05:59 | 只看該作者
The Genetics of Impulsivity: A Synthesis of Findings in Humans and Rodent Modelsogical disorders such as pathological gambling, drug addiction, attention deficit hyperactivity disorder, and Parkinson’s disease. Given the central role of impulsivity in these and other brain disorders there has been widespread interest in elucidating the neurobiological mechanisms and particularl
地板
發(fā)表于 2025-3-22 06:36:55 | 只看該作者
The Neurobiology and Genetics of Affiliation and Social Bonding in Animal Models. Although very little is known regarding the underlying neurobiological mechanisms influencing the development of human relationships, studies using animal models have gained insights into the regulation of this process in other species. In this chapter we will discuss several animal models that ha
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Genetic Models of Alzheimer’s Disease: The Influence of Apolipoprotein E allele Isoforms on Behaviou, presenilin 1, presenilin 2 and the apolipoprotein E (APOE) genes. We focus here on the behavioural impact in laboratory animals of polymorphisms in the APOE gene. In humans, this gene presents in the form of three allele variants (ε2, ε3 and ε4), with the ε4 polymorphism conferring a significantly
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發(fā)表于 2025-3-23 00:27:40 | 只看該作者
Social Endophenotypes in Mouse Models of Psychiatric Diseasespectrum disorders (ASDs) and schizophrenia, are impairments in socio-communicative behavior. These impairments have been proposed as candidate endophenotypes of disease processes, being present in prodromal and active stages of disease, as well as in undiagnosed relatives. The genetic bases for the
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發(fā)表于 2025-3-23 09:32:38 | 只看該作者
Animal Models of Addiction: Genetic Influencesrstanding of the role genes play in the vulnerability to such compulsive behaviors. Rodent models, in particular, have shown that traits such as impulsivity and high sweet consumption, among others, are under strong genetic influence and positively associated with drug intake, similar to human popul
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