Titlebook: Analytical Use of Fluorescent Probes in Oncology; Elli Kohen,Joseph G. Hirschberg Book 1996 Springer Science+Business Media New York 1996

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Information - Organisation - Produktion emitted and scattered light from tissues show potential in the medical arena. Optical spectroscopy offers exciting possibilities for novel . diagnostic and therapeutic approaches. The foundation for optical spectroscopy has been evolving since its beginnings over fifty years ago. Fluorescence and R

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https://doi.org/10.1007/978-3-658-15223-9ts may not be representative of events in individual cells. For this reason, the study of individual cells as they respond to imposed stresses and stimuli is desirable. Recent advances in microscope optics, video cameras, computer technology and fluorophore chemistry increasingly permit such measure

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https://doi.org/10.1007/978-94-009-7401-2However, the low specificity of P2 delivery to tumor tissues and the lack of light absorption of the mixture of porphyrins constituting P2 in the 650 – 800 nm range, where tissues maximally transmit precludes the use of PDT for large tumor masses. In the case of skin tumors, selectivity has been rec

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Giovannina Albano,Umberto Dello Iaconol death, as part of the developmental process. It is often referred to as programmed cell death. Apoptosis can be considered as the ‘natural’ mode of cell death, as opposed to death by necrosis which occurs during, for example, tissue injury. The importance of apoptosis in the development and mainte

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https://doi.org/10.1007/978-3-319-90790-1ex and may vary depending on the cells involved. We have developed hydrodynamic assays that mimic conditions in the microcirculation to study metastatic tumor cell interactions with endothelial cells and their underlying extracellular matrix. Acquisition and analysis of data are computerized, enabli

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Giovannina Albano,Umberto Dello Iaconohe clinician. Techniques of flow cytometry, which have developed in the last 30 years, have allowed for the rapid assessment of the cell cycle kinetics of large numbers of individual cells. These techniques can provide information on cell volume, DNA and protein content as well as more sophisticated

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https://doi.org/10.1007/978-3-319-90790-1r heterogeneity that constitutes a considerable challenge to the flow cytometric analysis of prognostic parameters. While multi-site sampling can circumvent the effect of stemline heterogeneity (2), the solution to the problem of cellular heterogeneity is less straightforward, and has, until relativ