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Titlebook: An Introduction to Toxicology; Philip C. Burcham Textbook 2014 Springer-Verlag London 2014 Apoptosis.carcinogen.epidemiology.organ.tobacco

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發(fā)表于 2025-3-21 19:03:47 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱An Introduction to Toxicology
影響因子2023Philip C. Burcham
視頻videohttp://file.papertrans.cn/156/155514/155514.mp4
發(fā)行地址A readable yet up-to-date volume to introduce the discipline of toxicology.Illustrations that “unpack” the concepts being discussed in the text.The author is an academic researcher with extensive teac
圖書封面Titlebook: An Introduction to Toxicology;  Philip C. Burcham Textbook 2014 Springer-Verlag London 2014 Apoptosis.carcinogen.epidemiology.organ.tobacco
影響因子.This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. .An Introduction to Toxicology. is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ?.?.
Pindex Textbook 2014
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ext.The author is an academic researcher with extensive teac.This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest
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Second Opinion bei Instabilit?tsomarthrose electrophile. Alcohol also undergoes nonoxidative metabolism to form such conjugative metabolites as ethyl-glucuronide, ethyl-sulfate and fatty acid ethyl esters. These metabolites find growing use as biomarkers of alcohol intake and appear especially useful during the diagnosis of foetal alcohol syndrome.
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Core Concepts in Toxicology,ctions between chemicals in complex ‘real-world’ exposure scenarios involving simultaneous exposure to more than one substance is also considered. The role of lifestyle factors in shaping individual susceptibility to chemical toxicity is also highlighted, as is the timing of the manifestation of toxicity following toxicant exposure.
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Target-Organ Toxicity: Liver and Kidney,ty, while also surveying typical toxic responses in these organs (e.g. steatosis, fibrosis, cancer). The diverse mechanisms underlying excretory organ toxicity are illustrated for such classic toxicants as azidothymidine, carbon tetrachloride, paracetamol, troglitazone, cylindrospermopsin and trichloroethylene.
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978-1-4471-7256-7Springer-Verlag London 2014
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