Titlebook: Alzheimer’s Disease; Methods and Protocol Jerold Chun Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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https://doi.org/10.1007/978-3-663-20308-7es and functional states in both healthy and diseased brains. To exploit fully the technologies available for such studies, one must extract and isolate pure nuclei from unfixed postmortem tissue while preserving the molecules to be interrogated. Currently, nuclei are necessary substitutes for indiv

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https://doi.org/10.1007/978-3-663-06775-7rains. The method is suitable for brain slices consisting of both gray and white matter..The ability to concomitantly isolate vascular cells with glial cells provides the opportunity to investigate multiple cell types originating from the same donor. This represents a novel approach for . research,

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