Titlebook: Alternatives to Animal Testing; Proceedings of Asian Hajime Kojima,Troy Seidle,Horst Spielmann Conference proceedings‘‘‘‘‘‘‘‘ 2019 The Edit

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Forschungsdesign und methodisches Vorgehen,for formulations and 41% for AIs using the GHS. Underprediction of dermal hazard was 1% for formulations and 3% for AIs using the EPA system and 1% for formulations and 3% for AIs using the GHS. While concordance overall was modest, the very low underprediction rates show that acute oral hazard cate

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https://doi.org/10.1007/978-3-642-92228-2lementation of 3Rs for some vaccines when distributed worldwide. This reinforces the need for enhancing international harmonization and cooperation efforts..In this chapter, we review the use of laboratory animals in human vaccines research and quality control and describe the vaccine manufacturing

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https://doi.org/10.1007/978-3-642-47800-0so developed a new prediction system named “CARCINOscreen.” for evaluating the carcinogenic potentials of chemicals using the gene expression profiles of liver and kidney tissues from rats after a 28-day repeated administration. The prediction system could predict the carcinogenicity potential of a

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https://doi.org/10.1007/978-3-642-47800-0mpound’s toxicity level and for establishing a prediction model that utilizes those endpoints. The EB area-based toxicity test (EBT) is an animal-free, novel drug screening system that can be useful in evaluating of various embryotoxic chemicals within a short time.

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