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Titlebook: Airways Smooth Muscle; Structure, Innervati David Raeburn (Department Head),Mark A. Giembycz ( Book 1994 Birkh?user Verlag 1994 asthma.cell

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發(fā)表于 2025-3-21 17:02:20 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Airways Smooth Muscle
期刊簡稱Structure, Innervati
影響因子2023David Raeburn (Department Head),Mark A. Giembycz (
視頻videohttp://file.papertrans.cn/152/151895/151895.mp4
學(xué)科分類Respiratory Pharmacology and Pharmacotherapy
圖書封面Titlebook: Airways Smooth Muscle; Structure, Innervati David Raeburn (Department Head),Mark A. Giembycz ( Book 1994 Birkh?user Verlag 1994 asthma.cell
影響因子Many factors may influence the release of neurotransmitters from airway nerves [1]. This is likely to be important in physiological control of airway functions and may be particularly relevant in airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD). Neural elements in airways interact in a complex manner and the activation of certain neural pathways may profoundly influence the release of transmitters from other neural pathways. Similarly inflamma- tory mediators released from inflammatory cells in the airways may also modulate neurotransmitter release. There are marked differences be- tween species in airway innervation and in neuromodulatory effects and, wherever possible, studies in human airways have been emphasised, although information on neuromodulation in human airways is some- what limited at present. Release of neurotransmitters from nerve terminals occurs via a Ca2+- dependent secretion evoked by a nerve action potential, but may also be evoked experimentally by a high extracellular K + concentration which directly depolarises the nerve terminal membrane. Modulation refers to the alteration of neurotransmitter release, which may either be incr
Pindex Book 1994
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Role of the Sympathetic Nervous System and Endogenous Catecholamines in the Regulation of Airways Sn the pathophysiology of airway diseases, particularly asthma, and in their treatment. Alpha and . adrenoceptors are widely distributed throughout the lung but are particularly prominent on airways smooth muscle in all species. Szentivanyi’s hypothesis [1] that . adrenoceptor hyporesponsiveness migh
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發(fā)表于 2025-3-22 01:23:17 | 只看該作者
Parasympathetic Innervation of Airways Smooth Muscle,smission was firmly established [3, 4] studies carried out in isolated lungs and in the lungs of dead animals demonstrated that electrical stimulation of the vagus nerves elicited “pneumoconstriction”, or what we now recognize were contractions of the bronchial musculature and thus constriction of t
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Airways Ganglia,edited with the first description of airways ganglia (referenced by Larsell, [4]). Larsell [4] recounts the contributions of several studies conducted in the late 1800s describing airways ganglia. The camera lucida drawing in these early papers, as well as those that appear in the early 1900s by Lar
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Excitatory Nonadrenergic, Noncholinergic Innervation of Airways Smooth Muscle: Role of Peptides,s optimised. Smooth muscle is regulated by local homeostatic mechanisms, but also neural and humoral mediators contribute to control of muscle tone. Pronounced spontaneous rhythmic contractions have been described in cultured human foetal lung tissue [1] and some myogenic activity is present also in
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發(fā)表于 2025-3-22 15:06:25 | 只看該作者
Inhibitory Nonadrenergic, Noncholinergic Innervation of Airways Smooth Muscle: Role of Vasoactive Ially with opposing excitatory and inhibitory actions. This view has been challenged by the findings of non-adrenergic, non-cholinergic (NANC) components in the regulation of . the cardiovascular, gas- trointestinal and urogenital functions [1]. The airways receive a dense supply of cholinergic nerve
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Vagal Reflexes,ement if the latter are strong. Thus it is not surprising that a very large number of sensory inputs to the central nervous system affect tracheobronchial smooth muscle tone. These reflexes have been studied mainly in experimental animals with inputs made as pure as possible, and motor responses iso
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