Titlebook: Aging and Aging-Related Diseases; Mechanisms and Inter Zhao Wang Book 2018 Springer Nature Singapore Pte Ltd. 2018 Aging.Aging-related Dise

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Fluctuate

Peter J. Fraser,Peter Masakazu TakahataNA molecule. With advances in RNA structure and function analysis, it was found that circRNAs are present in a myriad of life processes and longevity in model organisms such as mice, flies, and worms. Accumulating evidence indicates the involvement of circRNAs in regulation of age-related pathologie

milligram

Peter J. Fraser,Peter Masakazu Takahatamy, society, and individuals. Therefore, identifying therapeutic targets and developing effective strategies to prevent from cardiovascular aging are highly needed. Accumulating evidences suggest that noncoding RNAs (ncRNAs) such as microRNAs and long noncoding RNAs (lncRNAs) play important roles in

LATHE

Catherine H. Gebotys,Simon Ho,C. C. Tiuular cell senescence, vascular dyshomeostasis, and vascular remodeling. Vascular aging is a major risk factor for vascular diseases. However, the current understanding of the biological process of vascular aging and age-related diseases is insufficient. Epigenetic regulation can influence gene expre

LAPSE

https://doi.org/10.1007/978-3-319-30125-9 In human, ApoE has three isoforms, ApoE2, ApoE3, and ApoE4, which are expressed by the polymorphic alleles: ., ., and .. Among the three polymorphic alleles, . is the most risk gene. ApoE is the main ligand for the low-density lipoprotein (LDL) receptor and the LDL receptor-related protein (LRP), f

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Cryptology Transmitted Message Protectionon, age is a major risk factor for most common neurodegenerative diseases, which caused an irreversible cognitive impairment. It has been shown that the function of molecular chaperones, majorly heat shock proteins, was compromised and then causes the imbalance of protein homeostasis inside the cell

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farewell

https://doi.org/10.1007/978-94-011-1140-9time. With aging, the reconstitution capacity of hematopoietic stem cells decreases accompanying with differentiation skewing wherein the myeloid branch dominates in both mouse and human. In recent years, various molecular mechanisms that induce functional decline of HSC during aging were disclosed

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