Titlebook: Advances in Pain Research: Mechanisms and Modulation of Chronic Pain; Bai-Chuang Shyu,Makoto Tominaga Book 2018 The Editor(s) (if applicab

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Inelasticity

Karl Oeljeklaus,Wolfgang Richthoferrecent advances in the artificial manipulation of central neuronal activity, such as those with optogenetics, it is now possible to address many unanswered questions regarding the molecular and cellular mechanisms underlying the plastic changes in this pathway and their role in the pain chronification process.

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https://doi.org/10.1007/978-3-642-20554-5ynaptic function. I also discuss the therapeutic potential of microglia from recent advances in the development of new drugs targeting microglia, which may facilitate translation from the bench to bedside.