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Titlebook: Advances in Molecular Biology and Targeted Treatment for AIDS; Ajit Kumar Book 1991 Plenum Press, New York 1991 AIDS.biology.development.e

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51#
發(fā)表于 2025-3-30 10:50:48 | 只看該作者
Debora Compare,Kok-Ann Gwee,Gerardo Nardonethe primary transcripts is necessary to generate subgenomic mRNAs (including . mRNA and additional mRNAs in the more complex retroviruses), a major fraction of the RNA transcripts are transported to the cytoplasm in an unspliced form, where they serve both as mRNA and as genomic RNA (Coffin, 1990; Stoltzfus, 1989).
52#
發(fā)表于 2025-3-30 15:52:10 | 只看該作者
53#
發(fā)表于 2025-3-30 18:24:32 | 只看該作者
https://doi.org/10.1007/978-3-319-16904-0 that TAR is a .-acting element which is located immediately downstream of the transcription start site, between nucleotides +1 and +59 (Dayton . al., 1986; Rosen .., 1986; Fisher .., 1986; Hauber .., 1987; Muesing .., 1987).
54#
發(fā)表于 2025-3-30 20:46:25 | 只看該作者
55#
發(fā)表于 2025-3-31 01:57:26 | 只看該作者
56#
發(fā)表于 2025-3-31 08:20:11 | 只看該作者
Debora Compare,Kok-Ann Gwee,Gerardo Nardonee host cell. For HIV, this reaction has provided the first effective target for anti-viral therapy. Following reverse transcription, viral DNA is stably integrated into the host cell genome. The study of integration is important since this event appears to be obligatory for efficient replication of
57#
發(fā)表于 2025-3-31 13:16:15 | 只看該作者
Debora Compare,Kok-Ann Gwee,Gerardo Nardone the provirus. The insertion event depends on at least one viral protein, the integration protein (IN), which is a product of the viral . gene. Mutations in the IN coding region of . result in integration-negative retroviruses that will no longer replicate.. The proviral DNA is identical to the prec
58#
發(fā)表于 2025-3-31 17:21:13 | 只看該作者
Environmental Factors and Lifestylesf genomic RNA. The enzyme purified from virions has been shown to consist of two polypeptides of molecular weights 66,000 and 51,000 (Hoffman .., 1985; Di Marzo Veronese ..,1986). The 66 kD subunit has both polymerase and RNase H activities. Like other retroviral reverse transcriptases, the associat
59#
發(fā)表于 2025-3-31 18:55:00 | 只看該作者
Debora Compare,Kok-Ann Gwee,Gerardo Nardonethe primary transcripts is necessary to generate subgenomic mRNAs (including . mRNA and additional mRNAs in the more complex retroviruses), a major fraction of the RNA transcripts are transported to the cytoplasm in an unspliced form, where they serve both as mRNA and as genomic RNA (Coffin, 1990; S
60#
發(fā)表于 2025-3-31 22:35:45 | 只看該作者
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