期刊全稱(chēng) | Admixture Dynamics, Natural Selection and Diseases in Admixed Populations | 影響因子2023 | Wenfei Jin | 視頻video | http://file.papertrans.cn/146/145001/145001.mp4 | 發(fā)行地址 | Nominated as an outstanding Ph.D. Thesis by Chinese Academy of Sciences, China.Illustrating signals of natural selection in African American ?.Advancing the understanding on the recent population admi | 學(xué)科分類(lèi) | Springer Theses | 圖書(shū)封面 |  | 影響因子 | .In this thesis, Dr. Jin presents the distribution of ancestral chromosomal segments in the admixed genome, which could provide the information needed to explore population admixture dynamics. The author derives accurate population histories of African Americans and Mexicans using genome-wide single nucleotide polymorphisms (SNPs) data. Mapping the genetic background facilitates the study of natural selection in the admixed population, and the author identifies the signals of selection in African Americans since their African ancestors left for America. He further demonstrates that many of the selection signals were associated with African American-specific high-risk diseases such as prostate cancer and hypertension, suggesting an important role these disease-related genes might have played in adapting to their new environment. Lastly, the author reveals the complexity of natural selection in shaping human susceptibility to disease. The thesis significantly advances our understanding of the recent population admixture, adaptation to local environment and its health implications.. | Pindex | Book 2015 |
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書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations影響因子(影響力) 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations影響因子(影響力)學(xué)科排名 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations網(wǎng)絡(luò)公開(kāi)度 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations網(wǎng)絡(luò)公開(kāi)度學(xué)科排名 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations被引頻次 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations被引頻次學(xué)科排名 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations年度引用 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations年度引用學(xué)科排名 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations讀者反饋 
書(shū)目名稱(chēng)Admixture Dynamics, Natural Selection and Diseases in Admixed Populations讀者反饋學(xué)科排名 
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