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Titlebook: Adhesion?GPCRs; Structure to Functio Simon Yona,Martin Stacey Book 2010 The Editor(s) (if applicable) and The Author(s), under exclusive li

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樓主: minutia
21#
發(fā)表于 2025-3-25 06:02:19 | 只看該作者
Baukonstruktion - vom Prinzip zum Detailatrophilin 1 may control synapse maturation and exocytosis, whereas latrophilin 2 may be involved in breast cancer. Latrophilins may play different roles during development and in adult animals: thus, LAT-1 determines cell fate in early embryogenesis in . and controls neurotransmitter release in adu
22#
發(fā)表于 2025-3-25 10:34:07 | 只看該作者
Baukonstruktion - vom Prinzip zum Detailpairment. Although its ligand is currently unknown, VLGR1 is one of the few adhesion-GPCR family members in which mutations have been shown to be responsible for a human malady. Mutations in VLGR1 in humans result in one form (2C) of Usher syndrome, the most common genetic cause of combined blindnes
23#
發(fā)表于 2025-3-25 13:57:45 | 只看該作者
24#
發(fā)表于 2025-3-25 18:29:09 | 只看該作者
Lutz Franke,Gernod Deckelmann,Holger Stehrtis (CIA), a model for rheumatoid arthritis, was significantly ameliorated suggesting therapeutic value of CD97 targeting. CD97-deficient mice are essentially normal at steady state except for a mild granulocytosis, which increases under inflammatory conditions. Comparison of the consequences of ant
25#
發(fā)表于 2025-3-25 23:20:33 | 只看該作者
26#
發(fā)表于 2025-3-26 01:36:46 | 只看該作者
27#
發(fā)表于 2025-3-26 04:26:10 | 只看該作者
Baukonstruktion - vom Prinzip zum Detaillopmental biology. We have recently demonstrated that the putative neurotoxin receptor . defines a mechanism required for the alignment of cell division planes in the early embryo of the nematode .. Our analysis suggests that . is required for the propagation rather than the initial establishment of
28#
發(fā)表于 2025-3-26 10:09:50 | 只看該作者
Baukonstruktion - vom Prinzip zum Detaillysis site (GPS) has been identified as an intrinsic protein modification process of many adhesion-GPCRs. In recent years, the conserved cleavage site, molecular mechanism and the potential functional implication of the GPS proteolysis have been gradually unveiled. However, many aspects of this uniq
29#
發(fā)表于 2025-3-26 16:19:01 | 只看該作者
Baukonstruktion - vom Prinzip zum Detailes strong neuronal exocytosis in vertebrates. Latrophilin has an unusual structure consisting of two fragments that are produced by the proteolytic cleavage of the parental molecule and that behave independently in the plasma membrane. On binding an agonist, the fragments reassociate and send an int
30#
發(fā)表于 2025-3-26 18:18:43 | 只看該作者
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