Titlebook: Acute and Long-Term Side-Effects of Radiotherapy; Biological Basis and Wolfgang Hinkelbein,Gregor Bruggmoser,Michael Wann Conference procee

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Recent Results in Cancer Researchhttp://image.papertrans.cn/a/image/144429.jpg

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https://doi.org/10.1007/978-3-642-84892-6Early and Late Effects; Microvasculature; Normal Tissues; Time, Dose and Fractionation; chemotherapy; rad

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Biological Wastewater Treatment,Postmastectomy radiotherapy has played — and continues to play — a leading role in the clinical radiobiology of normal tissues. There are several reasons for this:

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Acute and Long-Term Side-Effects of Radiotherapy978-3-642-84892-6Series ISSN 0080-0015 Series E-ISSN 2197-6767

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https://doi.org/10.1007/978-981-97-6875-2 component. If the threshold of potential complete restitution is crossed, the pneumonitis will develop into pulmonary fibrosis (a scar) as a permanent residual (Gross 1977; Slanina et al. 1977; Westcott and Cole 1986; White 1975).

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https://doi.org/10.1007/978-981-97-4677-4 therapeutic purposes. The numerous experiments designed to elucidate the pathogenesis of radionecrosis pointed out changes occurring in either the stroma or the parenchyma of the tissues as the primary cause of late effects of ionizing radiation.

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Imen Souiden,Zaki Brahmi,Mohamed Nazih Omribnormalities were a consistent finding in radiation-damaged tissues (Gassmann 1899; Mühsam 1904). Since then there have been numerous pathology reports emphasizing the significance of vascular damage in association with late radiation effects. This led to a hypothesis, to a major degree conceived by

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Egemen Kaymaz,Filiz Senkal Sezere factor) to reach tolerance for late reactions. This is in contrast to repopulation in early-reacting tissues and in tumors (e.g., Withers et al. 1988). Nevertheless, time factors have been reported for late-reacting tissues, and even small values could sometimes be more important than in the cases