Titlebook: Activity-Based Protein Profiling; Benjamin F. Cravatt,Ku-Lung Hsu,Eranthie Weerapana Book 2019 Springer Nature Switzerland AG 2019 Penicil

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Activity-Based Protein Profiling978-3-030-11143-4Series ISSN 0070-217X Series E-ISSN 2196-9965

要塞

https://doi.org/10.1007/978-3-030-11143-4Penicillin-binding proteins; Poly-ADP-ribosylation; Host-virus interactions; Intramembrane proteases; Cy

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種子

Benjamin F. Cravatt,Ku-Lung Hsu,Eranthie WeerapanaProvides new insights into activity-based protein profiling (ABPP), which uses chemical probes to profile the functional state of enzymes in native biological systems.Focuses on the application of ABP

Spinous-Process

意見(jiàn)一致

https://doi.org/10.1007/978-3-642-61039-4Though their essentiality to life is clear, the mechanistic underpinnings of community structure, interactions, and functions are largely unexplored and in need of function-dependent technologies to unravel the mysteries. Activity-based protein profiling offers unprecedented molecular-level characte

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Entwicklung empirischer Methoden,obes. Using probes that target catalytically active enzymes, ABPP can rapidly define the functional proteome of a biological system. In recent years, this approach has been increasingly applied to globally profile enzymes active at the host–pathogen interface of microbial infections. From in vitro c

beta-carotene

Entwicklung empirischer Methoden,ods have provided new opportunities to explore protein fatty-acylation in microbial pathogens. Recent studies suggest that protein fatty-acylation is essential to survival and pathogenesis of eukaryotic pathogens such as parasites and fungi. Moreover, fatty-acylation in host cells can be exploited o