| 書目名稱 | Wnt Signaling | | 副標(biāo)題 | Volume 1: Pathway Me | | 編輯 | Elizabeth Vincan | | 視頻video | http://file.papertrans.cn/1031/1030010/1030010.mp4 | | 概述 | Records our progress to date in understanding the intricacies of Wnt signalling.Includes assays for and models of both canonical and non-canonical Wnt signalling pathways.Contributing authors are eith | | 叢書名稱 | Methods in Molecular Biology | | 圖書封面 |  | | 描述 | .Since their discovery, Wnt signaling molecules have been shown to control key events in embryogenesis, to maintain tissue homeostasis in the adult and, when aberrantly activated, to promote human degenerative diseases and cancer, thus making them a vital area of study. Wnt Signaling: Methods and Protocols examines both biochemical assays and vertebrate and invertebrate model systems to provide a point of reference to current molecular protocols and the diverse model systems employed to study this important signaling pathway. In Volume 1, Pathway Methods and Mammalian Models, assays to measure activation of the diverse Wnt signaling pathways are explored, along with a selection of models and strategies used to study mammalian Wnt/FZD fuction, from protein-protein interaction and simple cell line models to organoid cultures and mouse models. As a volume in the highly successful Methods in Molecular Biology? series, chapters contain readily reproducible laboratory protocols, complete with lists of necessary equipment and reagents and the Notes section, which reveals helpful troubleshooting tips...Comprehensive and cutting-edge, Wnt Signaling: Methods and Protocols collects the expert | | 出版日期 | Book 2008 | | 關(guān)鍵詞 | Activation; Calcium; Canonical Wnt/FZD signaling; Degenerative diseases and cancer; Embryogenesis; Non-ca | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-59745-249-6 | | isbn_softcover | 978-1-61737-841-6 | | isbn_ebook | 978-1-59745-249-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2008 |
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